O¹-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol

Base Information

• Chemical Name: O¹-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol
• CAS No.: 1413897-71-8
• Molecular Formula: C₃₂H₄₁NO₅S₂
• Molecular Weight: 583.813
• Mol file: 1413897-71-8.mol

Synonyms:O¹-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol

Chemical Property of O¹-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of O¹-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol

There total 1 articles about O¹-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol (1413897-66-1) + 4,4'-dimethoxytrityl chloride (40615-36-9) → O1-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol (1413897-71-8)

Guidance literature:

With pyridine; In acetonitrile; at 20 ℃; Inert atmosphere;

DOI:10.3390/molecules170910026

Reference yield: 56.0%

O1-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol (1413897-71-8) + 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine (124482-92-4,89992-70-1) → O1-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tertbutyldisulfanyl)ethylcarbonyl]-O3-[2-cyanoethyl-N,N-diisopropylaminophosphinyl]-L-threoninol (1413897-85-4,1413897-98-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 1.5h; Inert atmosphere; Cooling with ice;

DOI:10.3390/molecules170910026

Reference yield:

succinic acid anhydride (108-30-5) + O1-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol (1413897-71-8) → C36H45NO8S2 (1413897-76-3)

Guidance literature:

With pyridine; dmap; Inert atmosphere;

DOI:10.3390/molecules170910026

upstream raw materials:

N-[2-(tert-butyldisulfanyl)ethylcarbonyl]-L-threoninol

4,4'-dimethoxytrityl chloride

Downstream raw materials:

O¹-(4,4'-dimethoxytriphenylmethyl)-N-[2-(tertbutyldisulfanyl)ethylcarbonyl]-O³-[2-cyanoethyl-N,N-diisopropylaminophosphinyl]-L-threoninol

C₃₆H₄₅NO₈S₂