(2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester

Base Information

Chemical Name:(2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester
CAS No.:719308-15-3
Molecular Formula:C₂₂H₃₀N₂O₅
Molecular Weight:402.491
Hs Code.:

Synonyms:(2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester

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Chemical Property of (2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester

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Technology Process of (2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester

There total 5 articles about (2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1312310-57-8
C₂₂H₃₄N₂O₆

: 719308-15-3
(2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Dess-Martin periodane / dichloromethane

2: triphenylphosphine

With Dess-Martin periodane; triphenylphosphine; In dichloromethane;
DOI:10.1016/j.bmcl.2011.03.109

Reference yield:

: 16369-17-8,14438-11-0
2-amino-4-methylpentan-1-ol

: 719308-15-3
(2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane

2: Dess-Martin periodane / dichloromethane

3: triphenylphosphine

With 4-methyl-morpholine; benzotriazol-1-ol; Dess-Martin periodane; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triphenylphosphine; In dichloromethane;
DOI:10.1016/j.bmcl.2011.03.109

Reference yield:

: 30925-18-9
2-tert-butoxycarbonylamino-succinic acid 1-benzyl ester

: 719308-15-3
(2S)-2-tert-butoxycarbonylamino-3-(4-isobutyl-oxazol-2-yl)-propionic acid benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane

2: Dess-Martin periodane / dichloromethane

3: triphenylphosphine

With 4-methyl-morpholine; benzotriazol-1-ol; Dess-Martin periodane; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triphenylphosphine; In dichloromethane;
DOI:10.1016/j.bmcl.2011.03.109