4-CYANOPHENYLGLYOXAL HYDRATE

Base Information

• Chemical Name: 4-CYANOPHENYLGLYOXAL HYDRATE
• CAS No.: 19010-28-7
• Molecular Formula: C9H7NO3
• Molecular Weight: 177.159
• Hs Code.: 2926909090
• Mol file: 19010-28-7.mol

Synonyms:Benzonitrile,4-(dihydroxyacetyl)- (9CI);

Chemical Property of 4-CYANOPHENYLGLYOXAL HYDRATE

Chemical Property:

• Vapor Pressure: 5.86E-07mmHg at 25°C
• Boiling Point: 395.3 °C at 760 mmHg
• Flash Point: 192.9 °C
• PSA: 67.16000
• LogP: 0.87558

Purity/Quality:

98%min ^*data from raw suppliers

4-Cyanophenylglyoxal hydrate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-CYANOPHENYLGLYOXAL HYDRATE

There total 2 articles about 4-CYANOPHENYLGLYOXAL HYDRATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-cyanophenyl methyl ketone (1443-80-7) → 4-oxoacetyl-benzonitrile hydrate (19010-28-7)

Guidance literature:

With selenium(IV) oxide; water; In 1,4-dioxane; for 72h; Inert atmosphere; Reflux;

DOI:10.1016/j.bmcl.2008.09.047

Reference yield:

→ 4-oxoacetyl-benzonitrile hydrate (19010-28-7)

Guidance literature:

Aus 4-Cyanophenylchlormethylketon, 1)ueber das β-Oxononitron, 2)6n-HCl;

Reference yield: 99.0%

2,4-dimethyl-3-pentanol (600-36-2) + 4-oxoacetyl-benzonitrile hydrate (19010-28-7) → C16H21NO3

Guidance literature:

With C₂₃H₃₉N₃O₃; copper(II) bis(trifluoromethanesulfonate); In dichloromethane; at 20 ℃; for 3h; enantioselective reaction; Inert atmosphere; Molecular sieve; Schlenk technique;

DOI:10.1021/ja409859x

upstream raw materials:

4-cyanophenyl methyl ketone

Refernces

• 1、 Wang, Pan,Tao, Wen-Jie,Sun, Xiu-Li,Liao, Saihu,Tang, Yong. "A highly efficient and enantioselective intramolecular cannizzaro reaction under TOX/Cu(II) catalysis". supporting information. p. 16849 - 16852. Retrieved 2013/12/04.