(S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

Base Information

Chemical Name:(S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid
CAS No.:1220913-25-6
Molecular Formula:C₁₉H₂₅NO₃
Molecular Weight:315.412
Hs Code.:

Synonyms:(S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

Suppliers and Price of (S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

Chemical Property:

Purity/Quality:: 95%+ or 98%+ ^*data from raw suppliers

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Technology Process of (S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

There total 3 articles about (S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1470-99-1,1220913-24-5
cis-hexahydroisoindoline

: 865538-96-1
(S)-3-benzyldihydrofuran-2,5-dione

: 1220913-25-6
(S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

: 145375-43-5
mitiglinide

Guidance literature:: In toluene; at 45 - 47 ℃; Inert atmosphere;
DOI:10.14233/ajchem.2014.16137

Reference yield:

: 3972-36-9,884-33-3
(2S)-benzylsuccinic acid

: 1220913-25-6
(S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: acetic anhydride / dichloromethane / 40 - 45 °C / Inert atmosphere

2: toluene / 45 - 47 °C / Inert atmosphere

With acetic anhydride; In dichloromethane; toluene;
DOI:10.14233/ajchem.2014.16137

Reference yield:

: 3972-36-9,884-33-3
(2S)-benzylsuccinic acid

: 1220913-25-6
(S)-3-benzyl-4-((3aR,7aS)-1H-isoindol-2(3H,3aH,4H,5H,6H,7H,7aH)-yl)-4-oxobutanoic acid

: 145375-43-5
mitiglinide

Guidance literature:: Multi-step reaction with 2 steps

1: toluene; acetic anhydride / 1 h / Reflux

2: dichloromethane / 4 h / -10 - 5 °C

In dichloromethane; acetic anhydride; toluene;