3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene

Base Information

• Chemical Name: 3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene
• CAS No.: 70810-37-6
• Molecular Formula: C₁₈H₂₈O₃SSi
• Molecular Weight: 352.57
• Mol file: 70810-37-6.mol

Synonyms:3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene

Chemical Property of 3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene

There total 2 articles about 3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

tert-butyl(cyclohex-2-en-1-yloxy)dimethylsilane (72726-49-9) + Benzenesulfinic acid (618-41-7) → 3-(tert-butyldimethylsilyloxy)-2-(phenylsulfonyl)cyclohexene + 3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene (70810-37-6)

Guidance literature:

tert-butyl(cyclohex-2-en-1-yloxy)dimethylsilane; Benzenesulfinic acid; With N-iodo-succinimide; In dichloromethane; at 20 ℃;

With 1,4-diaza-bicyclo[2.2.2]octane; In tetrachloromethane; at 20 ℃;

DOI:10.1139/V06-051

Reference yield:

→ 3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene (70810-37-6)

Guidance literature:

entspr. β-Epoxysulfon (1b) 1. DBU, in DMF 2. Imidazol, tert-Butyldimethylsilylchlorid, Ausbeute;

DOI:10.1016/S0040-4039(01)85817-2

Reference yield: 30.0%

3-(tert-butyldimethylsilyloxy)-1-(phenylsulfonyl)cyclohexene (70810-37-6) + C12H17LiO4S → [(1S,2R,3R)-3-Benzenesulfonyl-2-(3-methoxy-2-methoxymethoxy-6-methylsulfanylmethoxymethyl-phenyl)-cyclohexyloxy]-tert-butyl-dimethyl-silane (76504-40-0)

Guidance literature:

In diethyl ether;

DOI:10.1016/S0040-4039(00)92786-2

upstream raw materials:

tert-butyl(cyclohex-2-en-1-yloxy)dimethylsilane

Benzenesulfinic acid

Downstream raw materials:

[(2R,3S)-2-Allyl-3-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-cyclohexanesulfonyl]-benzene

((3aS,4R,7aR)-7a-Benzenesulfonyl-2-methylene-octahydro-inden-4-yloxy)-tert-butyl-dimethyl-silane

((3aR,4R,7aS)-7a-Benzenesulfonyl-2-methylene-octahydro-inden-4-yloxy)-tert-butyl-dimethyl-silane

[(1S,2R,3R)-3-Benzenesulfonyl-2-(3-methoxy-2-methoxymethoxy-6-methylsulfanylmethoxymethyl-phenyl)-cyclohexyloxy]-tert-butyl-dimethyl-silane