4-CIS-FLUORO-L-PROLINAMIDE HYDROCHLORIDE

Base Information

• Chemical Name: 4-CIS-FLUORO-L-PROLINAMIDE HYDROCHLORIDE
• CAS No.: 426844-23-7
• Molecular Formula: C₅H₉FN₂O*ClH
• Molecular Weight: 168.599
• Hs Code.: 2933998090
• Mol file: 426844-23-7.mol

Synonyms:2-Pyrrolidinecarboxamide,4-fluoro-, monohydrochloride, (2S,4S)- (9CI); (2S,4S)-2-(Aminocarbonyl)-4-fluoropyrrolidinehydrochloride; (2S,4S)-4-Fluoro-2-pyrrolidinecarboxamide hydrochloride

Chemical Property of 4-CIS-FLUORO-L-PROLINAMIDE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 7.6E-05mmHg at 25°C
• Melting Point: 232°C
• Boiling Point: 337.3 °C at 760 mmHg
• Flash Point: 157.8 °C
• PSA: 55.12000
• Density: g/cm³
• LogP: 1.00280
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

(2S,4S)-4-Fluoropyrrolidine-2-carboxamidehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22-36-43
• Safety Statements: 26-36/37

MSDS Files:

Useful:

Technology Process of 4-CIS-FLUORO-L-PROLINAMIDE HYDROCHLORIDE

There total 9 articles about 4-CIS-FLUORO-L-PROLINAMIDE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl (2S,4S)-2-carbamoyl-4-fluoropyrrolidine-1-carboxylate (426844-22-6) → (2S,4S)-4-fluoropyrrolidine-2-carboxamide hydrochloride (426844-23-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 2h;

DOI:10.1016/j.bmc.2004.09.010

Reference yield: 98.0%

(2S,4S)-4-fluoropyrrolidine-2-carboxamide (748165-40-4) → (2S,4S)-4-fluoropyrrolidine-2-carboxamide hydrochloride (426844-23-7)

Guidance literature:

With hydrogenchloride; In diethyl ether; isopropyl alcohol; for 0.166667h;

Reference yield:

tert-butyl (2S,4R)-2-carbamoyl-4-fluoropyrrolidine-1-carboxylate (426844-26-0) → (2S,4R)-4-fluoropyrrolidine-2-carboxamide hydrochloride (426844-23-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃;

DOI:10.1016/j.bmc.2004.09.010

upstream raw materials:

tert-butyl (2S,4S)-2-carbamoyl-4-fluoropyrrolidine-1-carboxylate

(2S,4S)-1-(tert-butoxycarbonyl)-4-fluoropyrrolidine-2-carboxylic acid

(2S,4S)-4-fluoropyrrolidine-2-carboxamide

(2S,4S)-N-Fmoc-4-fluoropyrrolidine-2-carboxamide

Downstream raw materials:

(2S,4S)-N-chloroacetyl-4-fluoropyrrolidine-2-carboxamide

(2S,4S)-1-(2-chloroacetyl)-4-fluoropyrrolidine-2-carbonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 426844-23-7 4-CIS-FLUORO-L-PROLINAMIDE HYDROCHLORIDE

Send

Send

Metric Ton KG G Pound L ML

Send

Send