2-ACETYLAMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID

Base Information

Chemical Name:2-ACETYLAMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID
CAS No.:146664-08-6
Molecular Formula:C12H12N2O3
Molecular Weight:232.24
Hs Code.:
Mol file:146664-08-6.mol

Synonyms:DL-Phenylalanine,N-acetyl-4-cyano-;N-Acetyl-4-cyano-DL-phenylalanine;N-Acetyl-4-cyanophenylalanine;

Suppliers and Price of 2-ACETYLAMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Acetamido-3-(4-cyanophenyl)propanoicacid 97%
1g
$ 523.00

American Custom Chemicals Corporation
2-ACETYLAMINO-3-(4-CYANO-PHENYL)PROPIONIC ACID 97.00%
0.25G
$ 431.00

American Custom Chemicals Corporation
2-ACETYLAMINO-3-(4-CYANO-PHENYL)PROPIONIC ACID 97.00%
1G
$ 1617.00

Alichem
2-Acetamido-3-(4-cyanophenyl)propanoicacid
1g
$ 562.60

Total 8 raw suppliers

Chemical Property of 2-ACETYLAMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID

Chemical Property:

Boiling Point:535.138 °C at 760 mmHg
PKA:3.41±0.10(Predicted)
Flash Point:277.441 °C
PSA：90.19000
Density:1.276 g/cm³
LogP:1.08098

Purity/Quality:

97% ^*data from raw suppliers

2-Acetamido-3-(4-cyanophenyl)propanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-ACETYLAMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID

There total 4 articles about 2-ACETYLAMINO-3-(4-CYANO-PHENYL)-PROPIONIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17201-43-3
4-cyanobenzyl bromide

: 146664-08-6,193270-06-3
N-acetyl-4-cyano-D,L-phenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1: KI, NaOEt / dioxane / Heating

2: aq. NaOH / Heating

With sodium hydroxide; sodium ethanolate; potassium iodide; In 1,4-dioxane;
DOI:10.1016/S0960-894X(97)00115-7

Reference yield:

: 52117-01-8
N-acetyl-4-cyano-α-(ethoxycarbonyl)phenylalanine ethyl ester

: 146664-08-6,193270-06-3
N-acetyl-4-cyano-D,L-phenylalanine

Guidance literature:: With hydrogenchloride; sodium hydroxide; Yield given. Multistep reaction; 1.) EtOH, reflux, 18 h, 2.) EtOH;
DOI:10.1021/jm950112e

Reference yield:

: 104-85-8
para-methylbenzonitrile

: 146664-08-6,193270-06-3
N-acetyl-4-cyano-D,L-phenylalanine

Guidance literature:: Multi-step reaction with 2 steps

1.1: NBS; benzoylperoxide / CCl₄ / Heating

2.1: KI; NaOEt / dioxane / Heating

2.2: aq. NaOH / Heating

With N-Bromosuccinimide; sodium ethanolate; potassium iodide; dibenzoyl peroxide; In 1,4-dioxane; tetrachloromethane; 1.1: Bromination / 2.1: Condensation / 2.2: Hydrolysis;
DOI:10.1016/S0960-894X(99)00412-6