2-Pyridin-4-YL-1-(4-trifluoromethyl-phenyl)-ethanone

Base Information

Chemical Name:2-Pyridin-4-YL-1-(4-trifluoromethyl-phenyl)-ethanone
CAS No.:125996-71-6
Molecular Formula:C14H10 F3 N O
Molecular Weight:265.235
Hs Code.:2933399090
DSSTox Substance ID:DTXSID90472414
Mol file:125996-71-6.mol

Synonyms:125996-71-6;2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)-ETHANONE;2-pyridin-4-yl-1-[4-(trifluoromethyl)phenyl]ethanone;2-(pyridin-4-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one;2-(Pyridin-4-yl)-1-(4-(trifluoromethyl)phenyl)ethanone;ETHANONE, 2-(4-PYRIDINYL)-1-[4-(TRIFLUOROMETHYL)PHENYL]-;2-(PYRIDIN-4-YL)-1-[4-(TRIFLUOROMETHYL)PHENYL]ETHAN-1-ONE;Ethanone,2-(4-pyridinyl)-1-[4-(trifluoromethyl)phenyl]-;CEWANWLDCMJIOR-UHFFFAOYSA-N;SCHEMBL6282286;DTXSID90472414;AKOS012085324;AB16990;CS-0443120;A805454;2-(pyridin-4-yl)-1-(4-trifluoromethylphenyl)ethanone;2-Pyridin-4-yl-1-(4-trifluoromethyl-phenyl)ethanone

Suppliers and Price of 2-Pyridin-4-YL-1-(4-trifluoromethyl-phenyl)-ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-(Pyridin-4-yl)-1-[4-(trifluoromethyl)phenyl]ethan-1-one 98%
1 g
$ 1195.00

SynQuest Laboratories
2-(Pyridin-4-yl)-1-[4-(trifluoromethyl)phenyl]ethan-1-one 98%
250 mg
$ 443.00

J&W Pharmlab
2-Pyridin-4-yl-1-(4-trifluoromethyl-phenyl)-ethanone 98%
1g
$ 1380.00

J&W Pharmlab
2-Pyridin-4-yl-1-(4-trifluoromethyl-phenyl)-ethanone 98%
500mg
$ 740.00

J&W Pharmlab
2-Pyridin-4-yl-1-(4-trifluoromethyl-phenyl)-ethanone 98%
5g
$ 4880.00

American Custom Chemicals Corporation
2-PYRIDIN-4-YL-1-(4-TRIFLUOROMETHYL-PHENYL)ETHANONE 98.00%
1G
$ 2119.43

Total 10 raw suppliers

Chemical Property of 2-Pyridin-4-YL-1-(4-trifluoromethyl-phenyl)-ethanone

Chemical Property:

PSA：29.96000
LogP:3.52580
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:265.07144843
Heavy Atom Count:19
Complexity:302

Purity/Quality:

97% ^*data from raw suppliers

2-(Pyridin-4-yl)-1-[4-(trifluoromethyl)phenyl]ethan-1-one 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CC2=CC=NC=C2)C(F)(F)F

Technology Process of 2-Pyridin-4-YL-1-(4-trifluoromethyl-phenyl)-ethanone

There total 4 articles about 2-Pyridin-4-YL-1-(4-trifluoromethyl-phenyl)-ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-89-4
picoline

: 2967-66-0
methyl 4-(trifluoromethyl)benzoate

: 125996-71-6
2-(pyridin-4-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one

Guidance literature:: picoline; With lithium hexamethyldisilazane; at 0 ℃; for 0.5h;

methyl 4-(trifluoromethyl)benzoate;
DOI:10.1016/j.bmcl.2010.02.047

Reference yield:

: 108-89-4
picoline

: 455-18-5
4-CF₃C₆H₄CN

: 125996-71-6
2-(pyridin-4-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one

Guidance literature:: Yield given. Multistep reaction;

Reference yield:

: 108-89-4
picoline

: 583-02-8
ethyl 4-(trifluoromethyl)benzoate

: 125996-71-6
2-(pyridin-4-yl)-1-(4-(trifluoromethyl)phenyl)ethan-1-one

Guidance literature:: With sodium hexamethyldisilazane; Multistep reaction; 1.) THF, from 0 deg C to 10 deg C, 30 min, 2.) THF, RT, 3 h;
DOI:10.1021/jm00101a012