3-(4-Fluorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Base Information

Chemical Name:3-(4-Fluorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester
CAS No.:131488-15-8
Molecular Formula:C₁₅H₁₈FNO₂
Molecular Weight:263.312
Hs Code.:
European Community (EC) Number:634-344-3
ChEMBL ID:CHEMBL80515
Nikkaji Number:J1.972.618E
Mol file:131488-15-8.mol

Synonyms:2-carbomethoxy-3-(4-fluorophenyl)nortropane;2-CFPNT

Suppliers and Price of 3-(4-Fluorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(-)-2-BETA-CARBOMETHOXY-3-BETA-(4-FLUOROPHENYL)NORTROPANE 95.00%
5MG
$ 505.31

Total 9 raw suppliers

Chemical Property of 3-(4-Fluorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

Chemical Property:

Vapor Pressure:3.19E-05mmHg at 25°C
Boiling Point:355.2°C at 760 mmHg
Flash Point:168.6°C
PSA：38.33000
Density:1.17g/cm³
LogP:2.55160
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:263.13215698
Heavy Atom Count:19
Complexity:341

Purity/Quality:

99% ^*data from raw suppliers

(-)-2-BETA-CARBOMETHOXY-3-BETA-(4-FLUOROPHENYL)NORTROPANE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1C2CCC(N2)CC1C3=CC=C(C=C3)F

Technology Process of 3-(4-Fluorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester

There total 16 articles about 3-(4-Fluorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: (1R) 2β-carboxymethyl-3α-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane

: 131488-15-8
(1R)-2β-methoxycarbonyl-3α-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane

Guidance literature:: (1R) 2β-carboxymethyl-3α-(4-fluorophenyl)-8-methyl-8-azabicyclo[3.2.1]octane; With carbonochloridic acid 1-chloro-ethyl ester; at 100 ℃; for 1h;

With methanol; for 0.5h; Heating / reflux;

Reference yield: 95.0%

: 157008-48-5
(1R)-N-methyl-2β-methoxycarbonyl-3α-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane

: 306740-94-3,131488-15-8
(1R)-2β-methoxycarbonyl-3α-(4-fluorophenyl)-8-azabicyclo[3.2.1]-octane

Guidance literature:: (1R)-N-methyl-2β-methoxycarbonyl-3α-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane; With carbonochloridic acid 1-chloro-ethyl ester; at 100 ℃; for 1h;

With methanol; for 0.5h; Heating / reflux;