N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

Base Information

Chemical Name:N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane
CAS No.:303733-95-1
Molecular Formula:C₁₈H₁₉Cl₃FNO₄
Molecular Weight:438.711
Hs Code.:

Synonyms:N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

Suppliers and Price of N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

There total 3 articles about N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 50370-59-7
2β-carbomethoxy-3β-(4-fluorophenyl)tropane

: 17341-93-4
2,2,2-Trichloroethyl chloroformate

: 303733-95-1
N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

Guidance literature:

Reference yield:

: 352-13-6
4-flourophenylmagnesium bromide

: 303733-95-1
N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

Guidance literature:: Multi-step reaction with 2 steps

1: 11 percent / diethyl ether / 1 h / -20 °C

2: toluene / 1 h / 120 °C

In diethyl ether; toluene;
DOI:10.1021/jm00109a029

Reference yield:

: 50373-10-9
methyl ecgonidine

: 303733-95-1
N-(2,2,2-trichloroethylcarbamoyl)-2β-carbomethoxy-3β-(4'-fluorophenyl)nortropane

Guidance literature:: Multi-step reaction with 2 steps

1: 11 percent / diethyl ether / 1 h / -20 °C

2: toluene / 1 h / 120 °C

In diethyl ether; toluene;
DOI:10.1021/jm00109a029