Technology Process of C27H22ClN3O2
There total 7 articles about C27H22ClN3O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
6-bromo-2-methoxy-3-phenylquinoline;
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 0.166667h;
Inert atmosphere;
(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)-methanone;
In
tetrahydrofuran; hexane;
at -78 ℃;
Inert atmosphere;
With
water;
In
tetrahydrofuran; hexane;
at 20 ℃;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: pyridine / dichloromethane / 72 h / 20 °C
2.1: ethylmagnesium bromide / tetrahydrofuran; diethyl ether / 0.33 h / Inert atmosphere; Cooling with ice
2.2: 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere
3.2: -78 °C / Inert atmosphere
3.3: 20 °C / Inert atmosphere
With
pyridine; n-butyllithium; ethylmagnesium bromide;
In
tetrahydrofuran; diethyl ether; hexane; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: ethylmagnesium bromide / tetrahydrofuran; diethyl ether / 0.33 h / Inert atmosphere; Cooling with ice
1.2: 20 °C / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran; hexane / 0.17 h / -78 °C / Inert atmosphere
2.2: -78 °C / Inert atmosphere
2.3: 20 °C / Inert atmosphere
With
n-butyllithium; ethylmagnesium bromide;
In
tetrahydrofuran; diethyl ether; hexane;
