2-benzoylamino-1-(4-dimethylaminopyridin-3-yl)-3,3-dimethylbutyl benzyl ether

Base Information

Chemical Name:2-benzoylamino-1-(4-dimethylaminopyridin-3-yl)-3,3-dimethylbutyl benzyl ether
CAS No.:1094900-64-7
Molecular Formula:C₂₇H₃₃N₃O₂
Molecular Weight:431.578
Hs Code.:

Synonyms:2-benzoylamino-1-(4-dimethylaminopyridin-3-yl)-3,3-dimethylbutyl benzyl ether

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Chemical Property of 2-benzoylamino-1-(4-dimethylaminopyridin-3-yl)-3,3-dimethylbutyl benzyl ether

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Technology Process of 2-benzoylamino-1-(4-dimethylaminopyridin-3-yl)-3,3-dimethylbutyl benzyl ether

There total 1 articles about 2-benzoylamino-1-(4-dimethylaminopyridin-3-yl)-3,3-dimethylbutyl benzyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1094900-63-6
N-((1S,2S)-1-(4-(dimethylamino)pyridin-3-yl)-1-hydroxy-3,3-dimethylbutan-2-yl)benzamide

: 100-39-0
benzyl bromide

: 1094900-64-7
2-benzoylamino-1-(4-dimethylaminopyridin-3-yl)-3,3-dimethylbutyl benzyl ether

Guidance literature:: N-((1S,2S)-1-(4-(dimethylamino)pyridin-3-yl)-1-hydroxy-3,3-dimethylbutan-2-yl)benzamide; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.25h; Inert atmosphere;

benzyl bromide; In tetrahydrofuran; for 1.5h; Inert atmosphere;

With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; for 7h; Inert atmosphere;
DOI:10.1021/ja805541u