3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

Base Information

Chemical Name:3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol
CAS No.:1417801-97-8
Molecular Formula:C₃₃H₃₂O₆S
Molecular Weight:556.679
Hs Code.:

Synonyms:3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

Suppliers and Price of 3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

There total 23 articles about 3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1417801-95-6
5-isopropoxy-2,6-dimethoxy-3-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthrene

: 1417801-97-8
3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

Guidance literature:: With dichloromethane; pentamethylbenzene,; boron trichloride; In dichloromethane; for 0.5h; Inert atmosphere;
DOI:10.1021/ol303390a

Reference yield:

: 1417801-88-7
2-(4-methoxy-2-(3-(phenylsulfonyl)propyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1417801-97-8
3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium carbonate; water; potassium bromide; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane / toluene / 36 h / 65 °C / Inert atmosphere

2.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

2.2: 0.33 h / -78 °C / Inert atmosphere

2.3: 0.33 h / -78 - 0 °C / Inert atmosphere

3.1: pentamethylbenzene,; boron trichloride; dichloromethane / dichloromethane / 0.5 h / Inert atmosphere

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; dichloromethane; pentamethylbenzene,; water; boron trichloride; potassium carbonate; potassium bromide; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; toluene; 2.1: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/ol303390a

Reference yield:

: 1417801-89-8
5-isopropoxy-2,6-dimethoxy-3-(4-methoxy-2-(3-(phenylsulfonyl)propyl)phenyl)-9,10-dihydrophenanthrene

: 1417801-97-8
3,7-dimethoxy-6-(4-methoxy-2-(3-(phenylsulfonyl)but-3-en-1-yl)phenyl)-9,10-dihydrophenanthren-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: 0.33 h / -78 °C / Inert atmosphere

1.3: 0.33 h / -78 - 0 °C / Inert atmosphere

2.1: pentamethylbenzene,; boron trichloride; dichloromethane / dichloromethane / 0.5 h / Inert atmosphere

With dichloromethane; pentamethylbenzene,; boron trichloride; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; 1.1: |Horner-Wadsworth-Emmons Olefination;
DOI:10.1021/ol303390a