[(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid

Base Information

• Chemical Name: [(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid
• CAS No.: 212777-21-4
• Molecular Formula: C₄₆H₅₁N₃O₂₂
• Molecular Weight: 997.918
• Mol file: 212777-21-4.mol

Synonyms:[(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid

Chemical Property of [(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid

There total 2 articles about [(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

(2,3-dimethoxycarbonyloxy)benzoyl chloride (201296-89-1) + [6-(6-amino-hexylamino)-hexylamino]-acetic acid (454466-23-0) → [(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid (212777-21-4)

Guidance literature:

In sodium hydrogencarbonate; at 0 - 5 ℃; for 1h;

Reference yield:

1,8,15-triazapentadecane (143-23-7) → [(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid (212777-21-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / H₂ / Pd/C / methanol / 20 °C

2: 24 percent / aq. NaHCO₃ / 1 h / 0 - 5 °C

With hydrogen; palladium on activated charcoal; In methanol; sodium hydrogencarbonate;

Reference yield: 50.0%

ampicillin (69-53-4) + [(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid (212777-21-4) → C62H68N6O25S

Guidance literature:

[(2,3-bis-methoxycarbonyloxy-benzoyl)-(6-{(2,3-bis-methoxycarbonyloxy-benzoyl)-[6-(8-methoxycarbonyloxy-2,4-dioxo-4H-benzo[e][1,3]oxazin-3-yl)-hexyl]-amino}-hexyl)-amino]-acetic acid; With 4-methyl-morpholine; methyl chloroformate; In tetrahydrofuran; at -10 ℃; for 1h;

ampicillin; With triethylamine; In tetrahydrofuran;

upstream raw materials:

(2,3-dimethoxycarbonyloxy)benzoyl chloride

[6-(6-amino-hexylamino)-hexylamino]-acetic acid

1,8,15-triazapentadecane