Technology Process of 3-((2S,3R)-3-hydroxybutan-2-yloxy)phenyl benzoate
There total 1 articles about 3-((2S,3R)-3-hydroxybutan-2-yloxy)phenyl benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium carbonate;
In
N,N-dimethyl-formamide;
at 90 ℃;
- Guidance literature:
-
3-((2S,3R)-3-hydroxybutan-2-yloxy)phenyl benzoate;
With
lithium hydrochloride monohydrate; water;
In
tetrahydrofuran;
at 20 ℃;
With
hydrogenchloride;
In
tetrahydrofuran; water;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: water; lithium hydrochloride monohydrate / tetrahydrofuran / 20 °C
2: 1H-imidazole / dichloromethane / 20 °C
3: 4,4'-di-tert-butyl-2,2'-bipyridine; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer / tert-butyl methyl ether / 16 h / 100 °C / Inert atmosphere; Microwave irradiation; Sealed tube
4: water; sodium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / acetonitrile / 0.5 h / 140 °C / Inert atmosphere; Microwave irradiation
5: N,N-dimethyl-formamide / 120 °C / Sealed tube
With
1H-imidazole; lithium hydrochloride monohydrate; water; sodium carbonate;
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; 4,4'-di-tert-butyl-2,2'-bipyridine;
In
tetrahydrofuran; dichloromethane; tert-butyl methyl ether; N,N-dimethyl-formamide; acetonitrile;
4: Suzuki Coupling;
