ISOBUTYL HYDROGEN METHYLPHOSPHONATE

Base Information

• Chemical Name: ISOBUTYL HYDROGEN METHYLPHOSPHONATE
• CAS No.: 1604-38-2
• Molecular Formula: C5H13 O3 P
• Molecular Weight: 152.13
• Hs Code.: 2931900090
• Mol file: 1604-38-2.mol

Synonyms:Phosphonicacid, methyl-, isobutyl ester (6CI,7CI,8CI); Phosphonic acid, methyl-,mono(2-methylpropyl) ester (9CI); Isobutyl methanephosphonate; Isobutylmethylphosphonate; Isobutyl methylphosphonic acid; Methylphosphonic acidisobutyl ester; i-BuMPA

Chemical Property of ISOBUTYL HYDROGEN METHYLPHOSPHONATE

Chemical Property:

• Vapor Pressure: 0.079mmHg at 25°C
• Boiling Point: 209.92°C at 760 mmHg
• PKA: 2.31±0.10(Predicted)
• Flash Point: 80.757°C
• PSA: 56.34000
• Density: 1.091g/cm³
• LogP: 1.47420
• Storage Temp.: ?20°C

Purity/Quality:

98%min ^*data from raw suppliers

ISOBUTYL HYDROGEN METHYLPHOSPHONATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,T
• Hazard Codes: F,T
• Statements: 11-23/24/25-39/23/24/25
• Safety Statements: 7-16-36/37-45

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ISOBUTYL HYDROGEN METHYLPHOSPHONATE

There total 4 articles about ISOBUTYL HYDROGEN METHYLPHOSPHONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

O-isobutyl S-[2-(diethylamino)ethyl]methylphosphonothioate → 2-(diethylamino)ethyl disulfide (589-32-2) + methylphosphonic acid isobutylester (1604-38-2) + 2-(diethylamine)ethanethiol (100-38-9)

Guidance literature:

With water; at 40 ℃; for 144h; Rate constant; other time;

Reference yield:

O-isobutyl S-[2-(diethylamino)ethyl]methylphosphonothioate → methylphosphonic acid isobutylester (1604-38-2) + 2-(diethylamine)ethanethiol (100-38-9)

Guidance literature:

With phosphoric acid; ethylene glycol; Product distribution; decomposition of O-isobutyl S-(2-N,N-diethylamino)ethyl methylthiophosphonate in ethylene glycol-aq.H₃PO₄ mixture; IR and MS study;

Reference yield:

O-isobutyl O'-(p-nitrophenyl) methylphosphonate (7364-83-2) → 4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + methylphosphonic acid isobutylester (1604-38-2)

Guidance literature:

With phosphotriesterase like lactonases from Deinococcus radiodurans; water; cobalt(II) chloride; at 30 ℃; pH=9; Reagent/catalyst; Kinetics;

DOI:10.1021/ja405911h

upstream raw materials:

O-isobutyl O'-(p-nitrophenyl) methylphosphonate

Downstream raw materials:

isobutyl methyl methylphosphonate

Refernces

• 1、 Meier, Monika M.,Rajendran, Chitra,Malisi, Christoph,Fox, Nicholas G.,Xu, Chengfu,Schlee, Sandra,Barondeau, David P.,Hoecker, Birte,Sterner, Reinhard,Raushel, Frank M.. "Molecular engineering of organophosphate hydrolysis activity from a weak promiscuous lactonase template". supporting information. p. 11670 - 11677. Retrieved 2013/09/02.
• 2、 Kuntsevich, A. D.,Shantrokha, A. V.,Bukreev, S. N.,Golovkov, V. F.,Morozik, Yu. I.,et al.. "Hydrolysis of O-Isobutyl S-2-(N,N-diethylamino)ethyl Methylphosphonate with Equimolar Amounts of Water". . p. 317 - 319. Retrieved 2007/10/03.