Technology Process of tert-butyl 4-bromo-3,5-dimethylphenethylcarbamate
There total 4 articles about tert-butyl 4-bromo-3,5-dimethylphenethylcarbamate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trifluoroacetic acid;
In
dichloromethane;
at 20 ℃;
for 12h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: n-butyllithium; isopropylmagnesium chloride / tetrahydrofuran; hexane / 2 h / 0 °C
1.2: 13 h / -40 - 20 °C
2.1: ozone / dichloromethane / -78 °C
2.2: -78 °C
2.3: 12 h / -78 - 20 °C
3.1: di-tert-butyl-diazodicarboxylate; tributylphosphine / dichloromethane / 2 h / -10 - 20 °C
4.1: trifluoroacetic acid / dichloromethane / 12 h / 20 °C
With
n-butyllithium; tributylphosphine; di-tert-butyl-diazodicarboxylate; isopropylmagnesium chloride; ozone; trifluoroacetic acid;
In
tetrahydrofuran; hexane; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ozone / dichloromethane / -78 °C
1.2: -78 °C
1.3: 12 h / -78 - 20 °C
2.1: di-tert-butyl-diazodicarboxylate; tributylphosphine / dichloromethane / 2 h / -10 - 20 °C
3.1: trifluoroacetic acid / dichloromethane / 12 h / 20 °C
With
tributylphosphine; di-tert-butyl-diazodicarboxylate; ozone; trifluoroacetic acid;
In
dichloromethane;
