phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester

Base Information

• Chemical Name: phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester
• CAS No.: 716349-05-2
• Molecular Formula: C₂₄H₂₉O₅P
• Molecular Weight: 428.465
• Mol file: 716349-05-2.mol

Synonyms:phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester

Chemical Property of phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester

Chemical Property:

Purity/Quality:

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Technology Process of phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester

There total 1 articles about phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

3,3-Dimethylbut-1-yne (917-92-0) + diethyl chlorophosphate (814-49-3) + benzil (134-81-6) → phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester (716349-05-2)

Guidance literature:

3,3-Dimethylbut-1-yne; With n-butyllithium; In tetrahydrofuran; at -78 - 20 ℃;

benzil; In tetrahydrofuran; at -78 - 20 ℃;

diethyl chlorophosphate; With triethylamine; In tetrahydrofuran; at -78 - 20 ℃; Further stages.;

DOI:10.1021/ja072446m

Reference yield: 90.0%

phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester (716349-05-2) → phosphoric acid 1-tert-butyl-4-oxo-3,4-diphenyl-buta-1,2-dienyl ester diethyl ester (716349-09-6)

Guidance literature:

silver tetrafluoroborate; In dichloromethane; at 20 ℃;

DOI:10.1021/ja072446m

Reference yield: 65.0%

phosphoric acid 1-benzoyl-4,4-dimethyl-1-phenyl-pent-2-ynyl ester diethyl ester (716349-05-2) → phosphoric acid 2-tert-butyl-4,5-diphenyl-furan-3-yl ester diethyl ester

Guidance literature:

With silver tetrafluoroborate; In 1,2-dichloro-ethane; at 60 ℃; for 16h;

DOI:10.1002/anie.200353535

upstream raw materials:

3,3-Dimethylbut-1-yne

diethyl chlorophosphate

benzil

Downstream raw materials:

phosphoric acid 1-tert-butyl-4-oxo-3,4-diphenyl-buta-1,2-dienyl ester diethyl ester