Technology Process of 4-(3-bromophenyl)butanehydrazide
There total 3 articles about 4-(3-bromophenyl)butanehydrazide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-(3-bromophenyl)-butyric acid;
With
Carbonyldiimidazole;
In
tetrahydrofuran;
for 1.5h;
With
hydrazine hydrate;
In
tetrahydrofuran;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium cyanide / N,N-dimethyl-formamide / 0.5 h / 45 °C
1.2: 3.33 h / 45 °C
2.1: hydrazine hydrate; potassium hydroxide; water / ethylene glycol / 195 °C
3.1: Carbonyldiimidazole / tetrahydrofuran / 1.5 h
3.2: 0.5 h
With
sodium cyanide; Carbonyldiimidazole; water; hydrazine hydrate; potassium hydroxide;
In
tetrahydrofuran; ethylene glycol; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrazine hydrate; potassium hydroxide; water / ethylene glycol / 195 °C
2.1: Carbonyldiimidazole / tetrahydrofuran / 1.5 h
2.2: 0.5 h
With
Carbonyldiimidazole; water; hydrazine hydrate; potassium hydroxide;
In
tetrahydrofuran; ethylene glycol;
