ETHYL BROMOACETATE-2,2-D2

Base Information

• Chemical Name: ETHYL BROMOACETATE-2,2-D2
• CAS No.: 14341-47-0
• Molecular Formula: C4H5 Br D2 O2
• Molecular Weight: 168.986
• Mol file: 14341-47-0.mol

Synonyms:Acetic-d2acid, bromo-, ethyl ester (8CI,9CI); Ethyl bromoacetate-d2

Chemical Property of ETHYL BROMOACETATE-2,2-D2

Chemical Property:

• PSA: 26.30000
• LogP: 0.94440

Purity/Quality:

99% ^*data from raw suppliers

ETHYL BROMOACETATE-2,2-D2 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL BROMOACETATE-2,2-D2

There total 4 articles about ETHYL BROMOACETATE-2,2-D2 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethyl [2]alcohol (925-93-9) + bromoacetic-2,2-d2 acid bromoanhydride (40897-88-9) → ethyl bromo-<2,2-2H2>acetate (14341-47-0)

Guidance literature:

Ambient temperature;

DOI:10.1021/jo00249a005

Reference yield: 89.0%

ethyl [2]alcohol (925-93-9) + 2-bromoacetic-d2 acid-d (14341-48-1) → ethyl bromo-<2,2-2H2>acetate (14341-47-0)

Guidance literature:

With sulfuric acid; In benzene; for 4.5h; Heating;

Reference yield:

ethanol (64-17-5) + 2-bromoacetic-d2 acid-d (14341-48-1) → ethyl bromo-<2,2-2H2>acetate (14341-47-0)

Guidance literature:

With hydrogen cation;

DOI:10.1016/S0040-4039(00)76954-1

upstream raw materials:

ethanol

2-bromoacetic-d₂ acid-d

ethyl [2]alcohol

bromoacetic-2,2-d2 acid bromoanhydride

Refernces

• 1、 Hogg,Schowen. "Synthetic procedures for deuterium labeled acetylcholine perchlorates". . p. 1620 - 1623. Retrieved 1974.
• 2、 Gould, Steven J.,Ju, Shyhchen. "Biosynthesis of acivicin. 3. Incorporation of ornithine and Nδ-hydroxyornithine". . p. 10166 - 10172. Retrieved 2007/10/02.