1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione

Base Information

Chemical Name:1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione
CAS No.:1303613-96-8
Molecular Formula:C₂₅H₂₀N₄O₃
Molecular Weight:424.459
Hs Code.:

Synonyms:1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione

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Chemical Property of 1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione

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Technology Process of 1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione

There total 4 articles about 1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 107-19-7
propargyl alcohol

: 3-azido-1-benzyl-1-phenylquinoline-2,4(1H,3H)-dione

: 1303613-96-8
1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione

Guidance literature:: With copper(ll) sulfate pentahydrate; copper; In dimethyl sulfoxide; at 20 ℃; for 2h; Darkness;
DOI:10.3390/molecules16054070

Reference yield:

: 83-13-6
diethyl 2-phenylmalonate

: 1303613-96-8
1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 4 steps

1: Heating; Neat (no solvent)

2: thionyl chloride

3: sodium azide

4: copper(ll) sulfate pentahydrate; copper / dimethyl sulfoxide / 2 h / 20 °C / Darkness

With thionyl chloride; sodium azide; copper(ll) sulfate pentahydrate; copper; In dimethyl sulfoxide;
DOI:10.3390/molecules16054070

Reference yield:

: 758640-21-0,103-32-2
N-Benzylaniline

: 1303613-96-8
1-benzyl-3-(4-(hydroxymethyl)-1H-1,2,3-triazol-1-yl)-3-phenylquinoline-2,4(1H,3H)-dione

Guidance literature:: Multi-step reaction with 4 steps

1: Heating; Neat (no solvent)

2: thionyl chloride

3: sodium azide

4: copper(ll) sulfate pentahydrate; copper / dimethyl sulfoxide / 2 h / 20 °C / Darkness

With thionyl chloride; sodium azide; copper(ll) sulfate pentahydrate; copper; In dimethyl sulfoxide;
DOI:10.3390/molecules16054070