N-Benzylaniline

Base Information

• Chemical Name: N-Benzylaniline
• CAS No.: 758640-21-0
• Molecular Formula: C₁₃H₁₃N
• Molecular Weight: 183.253
• Mol file: 758640-21-0.mol

Synonyms:N-Benzylaniline

Chemical Property of N-Benzylaniline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Benzylaniline

There total 575 articles about N-Benzylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

benzaldehyde (100-52-7) + aniline (62-53-3) → N-Benzylaniline (758640-21-0,103-32-2) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

benzaldehyde; aniline; at 25 ℃; for 0.166667h;

With sodium tetrahydroborate; boric acid; at 25 ℃; for 0.25h;

DOI:10.1016/j.tet.2005.04.039

Reference yield: 93.0%

aniline (62-53-3) + benzyl alcohol (100-51-6,185532-71-2) → N-Benzylaniline (758640-21-0,103-32-2) + benzylidene phenylamine (538-51-2) + benzaldehyde (100-52-7)

Guidance literature:

With PdAu alloy nanoparticles encapsulated inside MIL-100(Fe) cavities; In acetonitrile; for 24h; Reagent/catalyst; Irradiation; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1016/j.jcat.2018.02.033

Reference yield: 93.0%

benzaldehyde (100-52-7) + nitrobenzene (98-95-3,26969-40-4) → N-Benzylaniline (758640-21-0,103-32-2) + benzyl alcohol (100-51-6,185532-71-2)

Guidance literature:

With PdAg_1.7; hydrogen; In ethanol; at 20 ℃; for 4h; Reagent/catalyst; Time;

DOI:10.1039/c3cc00249g

upstream raw materials:

2-(benzyloxy)quinoline

aniline

Benzyl acetate

aniline hydrochloride

Downstream raw materials:

N-benzyl-N-(2-[4]pyridyl-ethyl)-aniline

1-benzyl-4-methylquinolin-2(1H)-one

N-benzyl-3-oxo-N-phenylbutanamide

N-benzyl-N-[2-(4,6-dimethyl-[2]pyridyl)-ethyl]-aniline

Refernces

• 1、 Liu, Ruihuan,Wang, Yikun,Weng, Yanmei,Yao, Caiping,Zhang, Yan,Zhu, Gangzhi,He, Xiaoai,Xu, Kangping,Tan, Guishan. "Iodine-Mediated One-Pot Synthesis of 2-(Piperazin-1-yl)pyrazine Derivatives from N -Alkyl Piperazines". . p. 1083 - 1086. Retrieved 2017.
• 2、 Li, Guangzhe,Yu, Guo,Wang, Chengdong,Morita, Taiki,Zhang, Xuhai,Nakamura, Hiroyuki. "Copper(i)-catalysed intramolecular hydroarylation-redox cross-dehydrogenative coupling ofN-propargylanilines with phosphites". . p. 113 - 116. Retrieved 2021/12/29.
• 3、 Zhu, Guanxin,Duan, Zheng-Chao,Zhu, Haiyan,Ye, Dongdong,Wang, Dawei. "Selective C-C bonds formation, N-alkylation and benzo[d]imidazoles synthesis by a recyclable zinc composite". supporting information. p. 266 - 270. Retrieved 2021/08/06.