α-ketoisovalerate

Base Information

• Chemical Name: α-ketoisovalerate
• CAS No.: 2507-77-9
• Molecular Formula: C₅H₇O₃
• Molecular Weight: 115.109
• Mol file: 2507-77-9.mol

Synonyms:α-ketoisovalerate

Chemical Property of α-ketoisovalerate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of α-ketoisovalerate

There total 1 articles about α-ketoisovalerate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8) + α-ketoglutarate (64-15-3) → α-ketoisovalerate (2507-77-9) + L-glutamate (154679-07-9,11070-68-1)

Guidance literature:

With pyridoxal 5-triphosphate; branched-chain-amino-acid transaminase from E_. coli; In phosphate buffer; at 298.15 ℃; pH=7.18 - 7.24; Product distribution; Thermodynamic data; Equilibrium constant; Enzymatic reaction;

DOI:10.1006/jcht.2000.0686

Reference yield: 97.0%

α-ketoisovalerate (2507-77-9) → L-valine (72-18-4,25609-85-2,7004-03-7,921-10-8)

Guidance literature:

With ammonium formate; tris hydrochloride; nicotinamide adenine dinucleotide; formate dehydrogenase; phenylalanine dehydrogenase; In water; at 30 ℃; for 24h;

Reference yield:

α-ketoisovalerate (2507-77-9) → 2-hydroxy-3-methylbutanoic acid (4026-18-0,17407-55-5,17407-56-6,600-37-3)

Guidance literature:

With 1,6-di-o-phosphonohex-2-ulofuranose; piperazine*HCl buffer; NADH; at 25 ℃; Rate constant; pH 6.0, reaction in the presence of L-lactate dehydrogenase from Bacillus stearothermophilus (BSLDH Q₁₀₂R) or other enzymes;

DOI:10.1021/ja00038a016

upstream raw materials:

L-valine

α-ketoglutarate

Downstream raw materials:

L-valine

2-hydroxy-3-methylbutanoic acid

α-ketoglutarate

isobutyraldehyde

Refernces