(4-Methylphenyl)(pyridin-2-yl)methanamine

Base Information

Chemical Name:(4-Methylphenyl)(pyridin-2-yl)methanamine
CAS No.:39930-13-7
Molecular Formula:C₁₃H₁₄N₂
Molecular Weight:198.268
Hs Code.:
European Community (EC) Number:873-177-2
ChEMBL ID:CHEMBL4590160
DSSTox Substance ID:DTXSID801276080
Nikkaji Number:J901.653H

Synonyms:(4-methylphenyl)(pyridin-2-yl)methanamine;39930-13-7;(4-methylphenyl)-pyridin-2-ylmethanamine;CHEMBL4590160;Pyridin-2-yl(p-tolyl)methanamine;DTXSID801276080;AKOS010037473;alpha-(4-Methylphenyl)-2-pyridinemethanamine;CS-0452206;EN300-190941;1-(4-methylphenyl)-1-(pyridin-2-yl)methanamine

Suppliers and Price of (4-Methylphenyl)(pyridin-2-yl)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 4 raw suppliers

Chemical Property of (4-Methylphenyl)(pyridin-2-yl)methanamine

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:198.115698455
Heavy Atom Count:15
Complexity:185

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(C2=CC=CC=N2)N

Technology Process of (4-Methylphenyl)(pyridin-2-yl)methanamine

There total 3 articles about (4-Methylphenyl)(pyridin-2-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 95898-82-1
C₁₃H₁₂N₂O

: 39930-13-7
1-(4-methylphenyl)-1-(2-pyridyl)methylamine

Guidance literature:: C₁₃H₁₂N₂O; With trifluoroacetic acid; zinc; at 20 ℃; for 48h;

With sodium hydroxide; water;
DOI:10.1021/jo900415y

Reference yield:

: 78539-88-5
2-(4-toluoyl)pyridine

: 39930-13-7
1-(4-methylphenyl)-1-(2-pyridyl)methylamine

Guidance literature:: Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium acetate / ethanol; water / 6 h / 100 °C

2: zinc; trifluoroacetic acid / 48.5 h / 20 °C

With hydroxylamine hydrochloride; sodium acetate; trifluoroacetic acid; zinc; In ethanol; water;
DOI:10.1016/j.cclet.2021.05.018

Reference yield:

: 1121-60-4
pyridine-2-carbaldehyde

: 4294-57-9
para-methylphenylmagnesium bromide

: 39930-13-7
1-(4-methylphenyl)-1-(2-pyridyl)methylamine

Guidance literature:: With Rink amine resin; water; trifluoroacetic acid; trimethyl orthoformate; Yield given. Multistep reaction; solid phase synthesis; 1) RT, 2) Et₂O, toluene, 60 deg C, 24 h, 3) CH₂Cl₂, RT, 5 h;
DOI:10.1016/S0040-4039(97)01639-0