(R)-1,2,4-BUTANETRIOL TRIMESYLATE

Base Information

• Chemical Name: (R)-1,2,4-BUTANETRIOL TRIMESYLATE
• CAS No.: 203515-83-7
• Molecular Formula: C₇H₁₆O₉S₃
• Molecular Weight: 340.397
• Mol file: 203515-83-7.mol

Synonyms:1,2,4-Butanetriol,trimethanesulfonate, (2R)- (9CI);1,2,4-Butanetriol, trimethanesulfonate, (R)-;

Chemical Property of (R)-1,2,4-BUTANETRIOL TRIMESYLATE

Chemical Property:

• Boiling Point: 638.2±50.0 °C(Predicted)
• PSA: 155.25000
• Density: 1.501±0.06 g/cm3(Predicted)
• LogP: 1.91610

Purity/Quality:

98% ^*data from raw suppliers

(R)-1,2,4-BUTANETRIOL TRIMESYLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1,2,4-BUTANETRIOL TRIMESYLATE

There total 2 articles about (R)-1,2,4-BUTANETRIOL TRIMESYLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(S)-1,2,4-butanetriol (42890-76-6,6810-31-7) + methanesulfonyl chloride (124-63-0) → (2S)-1,2,4-trimethanesulfonyloxybutane (99520-81-7,203515-83-7,108963-16-2)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃; for 2h; Yield given;

Reference yield:

→ methanesulphonic acid 3,4-bis-methanesulphonyloxy-butyl ester (203515-83-7,108963-16-2)

Guidance literature:

Reference yield:

[1-Amino-eth-(Z)-ylidene]-carbamic acid 4-nitro-benzyl ester (96405-08-2) + (2S)-1,2,4-trimethanesulfonyloxybutane (99520-81-7,203515-83-7,108963-16-2) → 3-(S)-methansulfonyloxy-1-(N-p-nitrobenzyloxycarbonylacetimidoyl)pyrrolidine (90505-38-7)

Guidance literature:

With ammonia; triethylamine; Yield given. Multistep reaction; 1.) EtOH, RT, 3 d, 2.) EtOH, CH₂Cl₂, RT, 6 h;

upstream raw materials:

(S)-1,2,4-butanetriol

methanesulfonyl chloride

Downstream raw materials:

3-(S)-methansulfonyloxy-1-(N-p-nitrobenzyloxycarbonylacetimidoyl)pyrrolidine

3-(S)-methansulfonyloxy-1-p-nitrobenzyloxycarbonylpyrrolidine