Technology Process of benzyl α-D-diazoacetate
There total 5 articles about benzyl α-D-diazoacetate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water-d2; potassium carbonate;
In
acetonitrile;
at 20 ℃;
for 2h;
Inert atmosphere;
DOI:10.1055/s-0032-1318136
- Guidance literature:
-
Benzyl acetate;
With
2,2,2-trifluoroethyl trifluoroacetate; LiHMDSA;
In
tetrahydrofuran;
With
water-d2; triethylamine;
In
acetonitrile;
With
deuteriated sodium hydroxide;
In
acetonitrile;
Further stages.;
DOI:10.1002/ejoc.200601095
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 5 h / Inert atmosphere; Reflux
2: triethylamine; 4-toluenesulfonyl azide / acetonitrile / 10 h / 20 °C / Cooling with ice
3: potassium hydroxide / acetonitrile; water / 1 h / 20 °C
4: [D]-sodium hydroxide; water-d2 / diethyl ether / 24 h / 20 °C
With
4-toluenesulfonyl azide; [D]-sodium hydroxide; water-d2; triethylamine; potassium hydroxide;
In
diethyl ether; water; acetonitrile;
DOI:10.1002/chem.201300047
