Benzyl diazoacetate

Base Information

Chemical Name:Benzyl diazoacetate
CAS No.:52267-51-3
Molecular Formula:C9H8N2O2
Molecular Weight:176.175
Hs Code.:
European Community (EC) Number:694-680-1
Nikkaji Number:J655.512H
Wikidata:Q61082104
Mol file:52267-51-3.mol

Synonyms:benzyl diazoacetate;BENZYL 2-DIAZOACETATE;52267-51-3;(E)-2-diazonio-1-(phenylmethoxy)ethenolate;BENZYL 2-DIAZOACETATE, CONTAINS 10% DCM AS STABILIZER;Diazoacetic acid benzyl ester;JBBKWIFIXPBQGZ-UHFFFAOYSA-N;AT25593;EN300-105155;Benzyl diazoacetate, contains ~10% dichloromethane as stabilizer

Suppliers and Price of Benzyl diazoacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Benzyl diazoacetate solution 10% in toluene
100ml
$ 281.00

Sigma-Aldrich
Benzyl diazoacetate solution 10% in toluene
25ml
$ 88.40

Sigma-Aldrich
Benzyl diazoacetate contains ~10% dichloromethane as stabilizer
5g
$ 88.10

Sigma-Aldrich
Benzyl diazoacetate contains ~10% dichloromethane as stabilizer
1 g
$ 27.60

Total 2 raw suppliers

Chemical Property of Benzyl diazoacetate

Chemical Property:

Refractive Index:n20/D1.504
Flash Point:7℃
PSA：63.69000
Density:0.894 g/mL at 25 °C
LogP:1.11146
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:176.058577502
Heavy Atom Count:13
Complexity:216

Purity/Quality:

10% in toluene ^*data from raw suppliers

Benzyl diazoacetate solution 10% in toluene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC(=O)C=[N+]=[N-]

Technology Process of Benzyl diazoacetate

There total 14 articles about Benzyl diazoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 14661-69-9
p-toluenesulfonylhydrazone glyoxylic acid chloride

: 100-51-6,185532-71-2
benzyl alcohol

: 52267-51-3
benzyl diazoacetate

Guidance literature:: p-toluenesulfonylhydrazone glyoxylic acid chloride; benzyl alcohol; With N,N-dimethyl-aniline; In dichloromethane; at 0 ℃; for 0.5h;

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1.5h; Further stages.;
DOI:10.1002/chem.200601692

Reference yield: 85.0%

: 2462-31-9
benzyl 2-aminoacetate hydrochloride

: 52267-51-3
benzyl diazoacetate

Guidance literature:: With sodium nitrite; In dichloromethane; water; at 0 ℃; for 1.53333h;
DOI:10.1016/j.tet.2009.05.045

Reference yield: 82.0%

: 5396-89-4
benzyl acetoacetate

: 52267-51-3
benzyl diazoacetate

Guidance literature:: benzyl acetoacetate; With 4-toluenesulfonyl azide; triethylamine; In acetonitrile; for 8h;

With lithium hydroxide; In water; acetonitrile; at 23 ℃;
DOI:10.1016/j.tet.2017.01.048