2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid

Base Information

Chemical Name:2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid
CAS No.:86000-31-9
Molecular Formula:C₂₂H₃₄O₅
Molecular Weight:378.509
Hs Code.:

Synonyms:2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid

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Chemical Property of 2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid

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Technology Process of 2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid

There total 4 articles about 2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 86000-30-8
methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate

: 86000-31-9
2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid

Guidance literature:: With sodium hydroxide; In methanol; Heating;

Reference yield:

: 86000-29-5
[4'-(2-Acetoxy-1-methyl-ethyl)-1,3,3-trimethyl-3',6'-dioxo-bicyclohexyl-1',4'-dien-2-yl]-acetic acid

: 86000-31-9
2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / H₂, aq. NaOH / Adams' catalyst / methanol / 72 h

2: 92 percent / 10percent aq. NaOH / methanol / Heating

With sodium hydroxide; hydrogen; platinum(IV) oxide; In methanol;

Reference yield:

: 81752-76-3,81768-72-1,86000-29-5
[(S)-4'-(2-Acetoxy-1-methyl-ethyl)-1,3,3-trimethyl-3',6'-dioxo-bicyclohexyl-1',4'-dien-2-yl]-acetic acid

: 86000-31-9,94063-48-6,94063-50-0
{(S)-2-[4-(2-Hydroxy-1-methyl-ethyl)-2,5-dimethoxy-phenyl]-2,6,6-trimethyl-cyclohexyl}-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) hydrogen, 2.) NaoH / 1.) PtO₂ / 1.) MeOH

2: aq. NaOH

With sodium hydroxide; hydrogen; platinum(IV) oxide;