methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate

Base Information

• Chemical Name: methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate
• CAS No.: 86000-30-8
• Molecular Formula: C₂₃H₃₆O₅
• Molecular Weight: 392.536
• Mol file: 86000-30-8.mol

Synonyms:methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate

Chemical Property of methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate

There total 2 articles about methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

[4'-(2-Acetoxy-1-methyl-ethyl)-1,3,3-trimethyl-3',6'-dioxo-bicyclohexyl-1',4'-dien-2-yl]-acetic acid (86000-29-5) + dimethyl sulfate (77-78-1) → methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate (86000-30-8)

Guidance literature:

With sodium hydroxide; hydrogen; platinum(IV) oxide; In methanol; for 72h;

Reference yield:

[(S)-4'-(2-Acetoxy-1-methyl-ethyl)-1,3,3-trimethyl-3',6'-dioxo-bicyclohexyl-1',4'-dien-2-yl]-acetic acid (81752-76-3,81768-72-1,86000-29-5) + dimethyl sulfate (77-78-1) → {(S)-2-[4-(2-Hydroxy-1-methyl-ethyl)-2,5-dimethoxy-phenyl]-2,6,6-trimethyl-cyclohexyl}-acetic acid methyl ester (86000-30-8,94063-49-7,94063-54-4)

Guidance literature:

With sodium hydroxide; hydrogen; platinum(IV) oxide; Multistep reaction; 1.) MeOH;

Reference yield: 92.0%

methyl 2-(4-(2-hydroxy-isopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoate (86000-30-8) → 2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid (86000-31-9)

Guidance literature:

With sodium hydroxide; In methanol; Heating;

upstream raw materials:

[4'-(2-Acetoxy-1-methyl-ethyl)-1,3,3-trimethyl-3',6'-dioxo-bicyclohexyl-1',4'-dien-2-yl]-acetic acid

dimethyl sulfate

[(S)-4'-(2-Acetoxy-1-methyl-ethyl)-1,3,3-trimethyl-3',6'-dioxo-bicyclohexyl-1',4'-dien-2-yl]-acetic acid

Downstream raw materials:

2-(4-(2-hydroxyisopropyl)-2,5-dimethoxyphenyl)-2,6,6-trimethylcyclohexylethanoic acid

{(S)-2-[4-(2-Hydroxy-1-methyl-ethyl)-2,5-dimethoxy-phenyl]-2,6,6-trimethyl-cyclohexyl}-acetic acid