3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

Base Information

Chemical Name:3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate
CAS No.:911663-34-8
Molecular Formula:C₂₁H₂₇NO₉
Molecular Weight:437.447
Hs Code.:

Synonyms:3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

Suppliers and Price of 3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

There total 4 articles about 3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 911663-30-4
N,N-bis(tert-butoxycarbonyl)-O-(tert-butoxycarbonyl)-L-tyrosine methyl ester

: 911663-34-8
3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

Guidance literature:: N,N-bis(tert-butoxycarbonyl)-O-(tert-butoxycarbonyl)-L-tyrosine methyl ester; With N-Bromosuccinimide; In tetrachloromethane; for 1.5h; Reflux; Inert atmosphere; Irradiation;

With silver nitrate; In acetone; at 20 ℃; for 4h;
DOI:10.1021/acs.orglett.0c02884

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 911663-34-8
3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: Na₂CO₃ / tetrahydrofuran; H₂O / 2 h / 20 °C

1.2: 100 percent / DMAP / acetonitrile / 12 h / 20 °C

2.1: NBS / CCl₄ / 0.75 h / Heating; irradiation

3.1: silver nitrate / acetone / 2 h / 20 °C

With N-Bromosuccinimide; sodium carbonate; silver nitrate; In tetrahydrofuran; tetrachloromethane; water; acetone;
DOI:10.1021/jo061159i

Reference yield:

: 1080-06-4
L-Tyr-OMe

: 911663-34-8
3-(tert-butyl) 4-methyl (4S,5R)-5-(4-((tert-butoxycarbonyl)oxy)phenyl)-2-oxazolidin-2-one-3,4-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: 100 percent / DMAP

2: NBS / CCl₄ / 0.75 h / Heating; irradiation

3: silver nitrate / acetone / 2 h / 20 °C

With dmap; N-Bromosuccinimide; silver nitrate; In tetrachloromethane; acetone;
DOI:10.1021/jo061159i