4-(Aminomethyl)pyrimidine

Base Information

Chemical Name:4-(Aminomethyl)pyrimidine
CAS No.:45588-79-2
Molecular Formula:C5H7 N3
Molecular Weight:109.131
Hs Code.:2933599090
European Community (EC) Number:670-337-1
DSSTox Substance ID:DTXSID40513326
Wikidata:Q72439536
Mol file:45588-79-2.mol

Synonyms:4-(Aminomethyl)pyrimidine;45588-79-2;pyrimidin-4-ylmethanamine;4-Pyrimidinemethanamine;4-Aminomethylpyrimidine;1-(pyrimidin-4-yl)methanamine;MFCD06796202;4-(Aminomethyl)-pyrimidine;C-pyrimidin-4-yl-methylamine;(pyrimidin-4-yl)methanamine;SCHEMBL244702;DTXSID40513326;AUHXBTKGPUVFCB-UHFFFAOYSA-N;CHEBI:229249;AMY15802;AKOS009130588;CS-W018555;DS-10664;PD049612;SY041990;A7178;FT-0647129;EN300-28281;J-513631;Z254526552

Suppliers and Price of 4-(Aminomethyl)pyrimidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(Aminomethyl)pyrimidine
1g
$ 790.00

Matrix Scientific
4-(Aminomethyl)pyrimidine 95+%
5g
$ 850.00

Matrix Scientific
4-(Aminomethyl)pyrimidine 95+%
1g
$ 300.00

Matrix Scientific
4-(Aminomethyl)pyrimidine 95+%
500mg
$ 195.00

Crysdot
4-(Aminomethyl)pyrimidine 98%
1g
$ 175.00

Crysdot
4-(Aminomethyl)pyrimidine 98%
250mg
$ 72.00

Crysdot
4-(Aminomethyl)pyrimidine 98%
5g
$ 545.00

Chemenu
4-(Aminomethyl)pyrimidine 98%
25g
$ 1590.00

Chemenu
4-(Aminomethyl)pyrimidine 98%
10g
$ 795.00

Chemenu
4-(Aminomethyl)pyrimidine 98%
5g
$ 547.00

Total 60 raw suppliers

Chemical Property of 4-(Aminomethyl)pyrimidine

Chemical Property:

Vapor Pressure:0.092mmHg at 25°C
Refractive Index:1.558
Boiling Point:224.323 °C at 760 mmHg
PKA:7.46±0.29(Predicted)
Flash Point:112.07 °C
PSA：51.80000
Density:1.138 g/cm³
LogP:0.63560
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
XLogP3:-1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:109.063997236
Heavy Atom Count:8
Complexity:64.7

Purity/Quality:

99% ^*data from raw suppliers

4-(Aminomethyl)pyrimidine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN=CN=C1CN

Technology Process of 4-(Aminomethyl)pyrimidine

There total 1 articles about 4-(Aminomethyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 25746-87-6
acetal dimethylique du pyrimidine-4 carboxaldehyde

: 45588-79-2
1-(pyrimidin-4-yl)methanamine

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) cc. H₂SO₄; 2.) NH₂OH / 1.) H₂O, 70 deg C, 1.5 h; 2.) H₂O, 12 h, r.t., pH=8-9

2: H₂ / 10percent Pd-C / methanol / 6 h / 760 Torr / Ambient temperature

With sulfuric acid; hydrogen; hydroxylamine; palladium on activated charcoal; In methanol;

Reference yield: 80.0%

: 45588-79-2
1-(pyrimidin-4-yl)methanamine

: 742106-26-9
N-{3-[(3,5-dimethylphenyl)sulfonyl]-5-chloro-1H-indole-2-carbonyl}-D,L-alanine

: 5-chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(1-oxo-1-((pyrimidin-4-ylmethyl)amino)propan-2-yl)-1H-indole-2-carboxamide

Guidance literature:: With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 25 ℃; for 12h;
DOI:10.1021/acs.jmedchem.6b01906

Reference yield: 77.0%

: 45588-79-2
1-(pyrimidin-4-yl)methanamine

: 473257-46-4
5-chloro-3-(3,5-dimethylphenyl-sulfonyl)indole-2-carboxylic acid

: 5-chloro-3-((3,5-dimethylphenyl)sulfonyl)-N-(pyrimidin-4-ylmethyl)-1H-indole-2-carboxamide

Guidance literature:: With (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; at 25 ℃; for 12h;
DOI:10.1021/jm5011622