4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane

Base Information

• Chemical Name: 4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane
• CAS No.: 113917-92-3
• Molecular Formula: C₃₆H₅₈N₄O₁₀S₂
• Molecular Weight: 771.009
• Mol file: 113917-92-3.mol

Synonyms:4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane

Chemical Property of 4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane

There total 2 articles about 4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1,2-bis-(2-bromo-ethoxy)-ethane (31255-10-4) + 7,16-bis<2-(p-tolylsulphonylamino)ethyl>-1,4,10-tetraoxa-7,16-diazacyclo-octadecane (76343-82-3) → 4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane (113917-92-3)

Guidance literature:

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; Heating;

Reference yield:

N-(p-toluenesulfonyl)aziridine (3634-89-7) → 4,13-bis(p-tolylsulphonyl)-7,10,19,22,27,30-hexaoxa-1,4,13,16-tetra-aza<14.8.8>dotriacontane (113917-92-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / acetonitrile / Heating

2: 84 percent / 45percent aq. NaOH, tetrabutylammonium iodide / Heating

With sodium hydroxide; tetra-(n-butyl)ammonium iodide; In acetonitrile;

upstream raw materials:

1,2-bis-(2-bromo-ethoxy)-ethane

7,16-bis<2-(p-tolylsulphonylamino)ethyl>-1,4,10-tetraoxa-7,16-diazacyclo-octadecane

N-(p-toluenesulfonyl)aziridine

Refernces

• 1、 Lukyanenko, Nikolai G.,Basok, Stepan S.,Filonova, Lyubov K.. "MACROHETEROCYCLES. PART 44. FACILE SYNTHESIS OF AZACROWN ETHERS AND CRYPTANDS IN A TWO-PHASE SYSTEM". . p. 3141 - 3148. Retrieved 2007/10/02.