2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

Base Information

Chemical Name:2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide
CAS No.:1239964-49-8
Molecular Formula:C₁₈H₁₉ClFN₃O₂S
Molecular Weight:395.885
Hs Code.:

Synonyms:2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

Suppliers and Price of 2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

There total 6 articles about 2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1239964-48-7
2-(4-chloro-3-methoxyphenyl)-2-methylpropanehydrazide hydrochloride

: 1544-68-9
4-fluorophenyl isothiocyanate

: 1239964-49-8
2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1.5h;

Reference yield:

: 850564-15-7
2-(4-Chloro-3-methoxy-phenyl)-2-methyl-propionitrile

: 1239964-49-8
2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

Guidance literature:: Multi-step reaction with 4 steps

1: sulfuric acid / 20 h / Reflux

2: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 15 h

3: hydrogenchloride / ethyl acetate; diethyl ether / 18 h / 0 - 20 °C

4: triethylamine / dichloromethane / 1.5 h / 0 - 20 °C

With hydrogenchloride; sulfuric acid; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane; ethyl acetate;

Reference yield:

: 1239963-78-0
2-(4-chloro-3-methoxyphenyl)-2-methylpropanoic acid

: 1239964-49-8
2-(2-(4-chloro-3-methoxyphenyl)-2-methylpropanoyl)-N-(4-fluorophenyl)hydrazine carbothioamide

Guidance literature:: Multi-step reaction with 3 steps

1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 15 h

2: hydrogenchloride / ethyl acetate; diethyl ether / 18 h / 0 - 20 °C

3: triethylamine / dichloromethane / 1.5 h / 0 - 20 °C

With hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; N-ethyl-N,N-diisopropylamine; In diethyl ether; dichloromethane; ethyl acetate;