(S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid

Base Information

Chemical Name:(S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid
CAS No.:1434873-96-7
Molecular Formula:C₂₅H₂₅N₅O₃S
Molecular Weight:475.571
Hs Code.:

Synonyms:(S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid

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Chemical Property of (S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid

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Technology Process of (S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid

There total 4 articles about (S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₆H₂₇N₅O₃S

: 1434873-96-7
(S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid

Guidance literature:: With water; sodium hydroxide; In methanol;

Reference yield:

: 7311-63-9
5-bromothiophene-2-carboxylic acid

: 1434873-96-7
(S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: n-butyllithium / tetrahydrofuran / -78 °C

2: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide

3: water; sodium hydroxide / methanol

With n-butyllithium; water; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

Reference yield:

: 1037091-21-6
5-(diphenylmethyl)thiophene-2-carboxylic acid

: 1434873-96-7
(S)-2-(5-benzhydrylthiophene-2-carboxamido)-5-(2-cyanoguanidino)pentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide

2: water; sodium hydroxide / methanol

With water; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In methanol; N,N-dimethyl-formamide;