1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate

Base Information

• Chemical Name: 1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate
• CAS No.: 957133-46-9
• Molecular Formula: C₁₈H₁₃F₃N₂O₄S
• Molecular Weight: 410.373
• Mol file: 957133-46-9.mol

Synonyms:1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate

Chemical Property of 1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate

There total 1 articles about 1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

1-benzyl-5-phenyl-1,2-dihydropyridazine-3,6-dione (957133-22-1) + trifluoromethylsulfonic anhydride (358-23-6) → 1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate (957133-46-9)

Guidance literature:

With pyridine; at 5 ℃; for 1h;

DOI:10.1016/j.tetlet.2007.09.013

Reference yield: 84.0%

1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate (957133-46-9) + 4-methoxyphenylboronic acid (5720-07-0) → 2-benzyl-6-(4-methoxyphenyl)-4-phenylpyridazin-3(2H)-one

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 100 ℃; for 0.333333h; microwave irradiation;

DOI:10.1016/j.tetlet.2007.09.013

Reference yield: 81.0%

1-benzyl-6-oxo-5-phenyl-1,6-dihydropyridazin-3-yl trifluoromethanesulfonate (957133-46-9) + 3,4-Dimethoxyphenylboronic acid (122775-35-3) → 2-benzyl-6-(3,4-dimethoxyphenyl)-4-phenylpyridazin-3(2H)-one

Guidance literature:

With sodium carbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,2-dimethoxyethane; water; at 100 ℃; for 0.333333h; microwave irradiation;

DOI:10.1016/j.tetlet.2007.09.013

upstream raw materials:

1-benzyl-5-phenyl-1,2-dihydropyridazine-3,6-dione

trifluoromethylsulfonic anhydride