(R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

Base Information

Chemical Name:(R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide
CAS No.:84274-46-4
Molecular Formula:C₁₇H₂₆N₂O₃
Molecular Weight:306.405
Hs Code.:

Synonyms:(R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

Suppliers and Price of (R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

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Chemical Property of (R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

Chemical Property:

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Technology Process of (R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

There total 4 articles about (R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84274-34-0
(Z)-2-Acetylamino-N-((S)-1-benzyloxymethyl-3-methyl-butyl)-3-phenyl-acrylamide

: 84274-46-4
(R)-2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

Guidance literature:: With hydrogen; <(Ph-CAPP)Rh(1,5-cyclooctadiene)>ClO4; In ethanol; at 40 ℃; for 42h; under 3800 Torr;
DOI:10.1246/cl.1982.1335

Reference yield:

: 84274-34-0
(Z)-2-Acetylamino-N-((S)-1-benzyloxymethyl-3-methyl-butyl)-3-phenyl-acrylamide

: 84274-46-4,84274-47-5
2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

Guidance literature:: palladium on activated charcoal; In ethanol; at 25 ℃; for 40h; under 760 Torr; Yield given;
DOI:10.1016/S0040-4020(01)82412-1

Reference yield:

: 88739-85-9
(S)-4-methyl-1-phenylmethoxy-2-pentylamine

: 84274-46-4,84274-47-5
2-Acetylamino-N-((S)-1-hydroxymethyl-3-methyl-butyl)-3-phenyl-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CHCl₃ / Ambient temperature

2: 10percent Pd-C / ethanol / 40 h / 25 °C / 760 Torr

With triethylamine; palladium on activated charcoal; In ethanol; chloroform;
DOI:10.1016/S0040-4020(01)82412-1