(4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

Base Information

Chemical Name:(4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate
CAS No.:1600565-41-0
Molecular Formula:C₂HF₃O₂*C₂₆H₁₈ClF₃N₄O
Molecular Weight:608.927
Hs Code.:

Synonyms:(4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

Suppliers and Price of (4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

There total 5 articles about (4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1600562-89-7
4-chloro-6-iodo-3-phenyl-2-(trifluoromethyl)quinoline

: 1599529-17-5
(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanone

: 76-05-1
trifluoroacetic acid

: 1600565-41-0
(4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

Guidance literature:: 4-chloro-6-iodo-3-phenyl-2-(trifluoromethyl)quinoline; With isopropylmagnesium chloride; In tetrahydrofuran; at -78 ℃; for 0.383333h;

(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanone; In tetrahydrofuran; at 20 - 50 ℃;

trifluoroacetic acid; In water; acetonitrile;

Reference yield:

: 350-92-5
1,1,1-Trifluoro-3-phenylpropan-2-one

: 1600565-41-0
(4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

Guidance literature:: Multi-step reaction with 3 steps

1.1: Eaton’s reagent / dichloromethane / 4 h / 100 °C / Sealed tube

2.1: trichlorophosphate / 1.75 h / 110 °C

3.1: isopropylmagnesium chloride / tetrahydrofuran / 0.38 h / -78 °C

3.2: 20 - 50 °C

With Eaton’s reagent; isopropylmagnesium chloride; trichlorophosphate; In tetrahydrofuran; dichloromethane;

Reference yield:

: 1600562-88-6
6-iodo-3-phenyl-2-(trifluoromethyl)quinolin-4-ol

: 1600565-41-0
(4-chloro-3-phenyl-2-(trifluoromethyl)quinolin-6-yl)(1-methyl-1H-imidazol-5-yl)(pyridin-2-yl)methanol trifluoroacetate

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 1.75 h / 110 °C

2.1: isopropylmagnesium chloride / tetrahydrofuran / 0.38 h / -78 °C

2.2: 20 - 50 °C

With isopropylmagnesium chloride; trichlorophosphate; In tetrahydrofuran;