5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

Base Information

Chemical Name:5-(pentafluorophenyl)imidazo[1,2-c]quinazoline
CAS No.:1418203-45-8
Molecular Formula:C₁₆H₆F₅N₃
Molecular Weight:335.236
Hs Code.:

Synonyms:5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

Suppliers and Price of 5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

Chemical Property:

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Technology Process of 5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

There total 3 articles about 5-(pentafluorophenyl)imidazo[1,2-c]quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1418203-55-0
5-(pentafluorophenyl)-2,3,5,6-tetrahydroimidazo[1,2-c]quinazoline

: 1418203-45-8
5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

Guidance literature:: With potassium permanganate; silica gel; In acetonitrile; at 20 ℃; for 16h; chemoselective reaction;
DOI:10.1055/s-0032-1316802

Reference yield:

: 1885-29-6
anthranilic acid nitrile

: 1418203-45-8
5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

Guidance literature:: Multi-step reaction with 3 steps

1: tetraphosphorus decasulfide / m-xylene / 40 h / Reflux; Inert atmosphere

2: acetonitrile / 48 h / 20 °C / Inert atmosphere

3: silica gel; potassium permanganate / acetonitrile / 16 h / 20 °C

With potassium permanganate; tetraphosphorus decasulfide; silica gel; In m-xylene; acetonitrile;
DOI:10.1055/s-0032-1316802

Reference yield:

: 28637-61-8
2-(2-aminophenyl)-4,5-dihydro-1H-imidazole

: 1418203-45-8
5-(pentafluorophenyl)imidazo[1,2-c]quinazoline

Guidance literature:: Multi-step reaction with 2 steps

1: acetonitrile / 48 h / 20 °C / Inert atmosphere

2: silica gel; potassium permanganate / acetonitrile / 16 h / 20 °C

With potassium permanganate; silica gel; In acetonitrile;
DOI:10.1055/s-0032-1316802