C₁₇H₁₃F₂N

Base Information

• Chemical Name: C₁₇H₁₃F₂N
• CAS No.: 566884-12-6
• Molecular Formula: C₁₇H₁₃F₂N
• Molecular Weight: 269.294
• Mol file: 566884-12-6.mol

Synonyms:C₁₇H₁₃F₂N

Chemical Property of C₁₇H₁₃F₂N

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₃F₂N

There total 5 articles about C₁₇H₁₃F₂N which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-fluoro-α-(4-fluorophenyl)benzeneacetonitrile (37742-99-7) + allyl bromide (106-95-6) → C17H13F2N (566884-12-6)

Guidance literature:

4-fluoro-α-(4-fluorophenyl)benzeneacetonitrile; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

allyl bromide; In tetrahydrofuran; at -78 - 20 ℃; for 16h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c7gc01992k

Reference yield:

allyl iodid (556-56-9) + 4-fluoro-α-(4-fluorophenyl)benzeneacetonitrile (37742-99-7) → C17H13F2N (566884-12-6)

Guidance literature:

4-fluoro-α-(4-fluorophenyl)benzeneacetonitrile; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

allyl iodid; In tetrahydrofuran; hexane; at -78 - 23 ℃; for 16h; Inert atmosphere;

DOI:10.1002/adsc.201400317

Reference yield:

4,4'-difluorobenzhydryl alcohol (365-24-2) → C17H13F2N (566884-12-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: molybdenum(V) chloride / dichloromethane / 0.25 h / 23 °C

1.2: 3 h / 23 °C

2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 0.5 h / -78 °C / Inert atmosphere

2.2: 16 h / -78 - 23 °C / Inert atmosphere

With n-butyllithium; molybdenum(V) chloride; diisopropylamine; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1002/adsc.201400317

upstream raw materials:

allyl iodid

4-fluoro-α-(4-fluorophenyl)benzeneacetonitrile

4,4'-difluorobenzhydryl alcohol

allyl bromide

Downstream raw materials:

2,2-bis(4-fluorophenyl)pent-4-en-1-ol