phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

Base Information

Chemical Name:phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside
CAS No.:258857-69-1
Molecular Formula:C₁₈H₂₉N₃O₂SSi
Molecular Weight:379.599
Hs Code.:

Synonyms:phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

Suppliers and Price of phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

There total 2 articles about phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 18162-48-6
tert-butyldimethylsilyl chloride

: 611210-53-8
phenyl 3-azido-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

: 258857-69-1
phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

Guidance literature:: With 1H-imidazole; In dichloromethane; at 40 ℃; for 24h;
DOI:10.1016/S0040-4020(03)00820-2

Reference yield:

: 108-98-5
thiophenol

: 258857-69-1
phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / BF₃*OEt₂ / 0.83 h / 0 °C

2: 94 percent / imidazole / CH₂Cl₂ / 24 h / 40 °C

With 1H-imidazole; boron trifluoride diethyl etherate; In dichloromethane;
DOI:10.1016/S0040-4020(03)00820-2

Reference yield:

: 258857-69-1
phenyl 3-azido-4-O-tert-butyldimethylsilyl-2,3,6-trideoxy-1-thio-D-arabinohexopyranoside

: 258857-76-0
2-Phenyl-quinoline-4-carboxylic acid 2-[(2R,4R,5S,6R)-5-(tert-butyl-dimethyl-silanyloxy)-4-dimethylamino-6-methyl-tetrahydro-pyran-2-yloxy]-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 79 percent / NBS; molecular sieves 4 Angstroem / acetonitrile / 1 h / 0 °C

2: H₂ / Pd/C / aq. methanol / 18 h / 25 °C

3: 90 percent / DCC; 4-DMAP / CH₂Cl₂ / 4.5 h / 0 °C

With dmap; N-Bromosuccinimide; 4 A molecular sieve; hydrogen; dicyclohexyl-carbodiimide; palladium on activated charcoal; In methanol; dichloromethane; acetonitrile; 1: Etherification / 2: Catalytic hydrogenation / 3: Esterification;
DOI:10.1002/(SICI)1521-3773(19991216)38:24<3733::AID-ANIE3733>3.0.CO;2-W