Technology Process of C28H36O8S2
There total 6 articles about C28H36O8S2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C19H26O6S;
With
triethylamine;
In
dichloromethane;
at 0 ℃;
for 0.166667h;
2-mesitylenesulphonyl chloride;
With
dmap;
In
dichloromethane;
at 20 ℃;
for 8h;
DOI:10.1021/ol303272w
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.33 h / -78 °C
1.2: 21 h / 20 °C
2.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 36 h
3.1: (S)-N-( p-dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide / ethanol; 1,2-dichloro-ethane / 0.17 h / 0 °C
3.2: 120 h / 4 °C
4.1: hydrogenchloride / 1,4-dioxane; water / 8 h / 20 °C
5.1: triethylamine / dichloromethane / 0.17 h / 0 °C
5.2: 8 h / 20 °C
With
hydrogenchloride; Hoveyda-Grubbs catalyst second generation; (S)-N-( p-dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; hexane; dichloromethane; water; 1,2-dichloro-ethane;
DOI:10.1021/ol303272w
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: toluene-4-sulfonic acid / dichloromethane / 14 h / 20 °C
2.1: lithium diisopropyl amide / tetrahydrofuran; hexane / 0.33 h / -78 °C
2.2: 21 h / 20 °C
3.1: Hoveyda-Grubbs catalyst second generation / dichloromethane / 36 h
4.1: (S)-N-( p-dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide / ethanol; 1,2-dichloro-ethane / 0.17 h / 0 °C
4.2: 120 h / 4 °C
5.1: hydrogenchloride / 1,4-dioxane; water / 8 h / 20 °C
6.1: triethylamine / dichloromethane / 0.17 h / 0 °C
6.2: 8 h / 20 °C
With
hydrogenchloride; Hoveyda-Grubbs catalyst second generation; (S)-N-( p-dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide; toluene-4-sulfonic acid; triethylamine; lithium diisopropyl amide;
In
tetrahydrofuran; 1,4-dioxane; ethanol; hexane; dichloromethane; water; 1,2-dichloro-ethane;
DOI:10.1021/ol303272w
