methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate

Base Information

• Chemical Name: methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate
• CAS No.: 1239317-22-6
• Molecular Formula: C₂₇H₃₅NO₅S
• Molecular Weight: 485.645
• Mol file: 1239317-22-6.mol

Synonyms:methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate

Chemical Property of methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate

There total 1 articles about methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2,4,6-triisopropylbenzene sulfonamide (105536-22-9) + (E)-methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate (105213-31-8) → methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate (1239317-22-6)

Guidance literature:

With titanium tetrachloride; triethylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/anie.201000755

Reference yield: 91.0%

methyl 4-(4-methoxyphenyl)-2-(2,4,6-triisopropylphenylsulfonylimino)but-3-enoate (1239317-22-6) + C30H22OS → (4S,5R)-methyl 5-benzoyl-4-(4-methoxyphenyl)-1-(2,4,6-triisopropylphenylsulfonyl)-4,5-dihydro-1H-pyrrole-2-carboxylate (1239317-31-7)

Guidance literature:

In dichloromethane; toluene; at -80 - 20 ℃; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/anie.201000755

upstream raw materials:

2,4,6-triisopropylbenzene sulfonamide

(E)-methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate

Downstream raw materials:

(4S,5R)-methyl 5-benzoyl-4-(4-methoxyphenyl)-1-(2,4,6-triisopropylphenylsulfonyl)-4,5-dihydro-1H-pyrrole-2-carboxylate