105213-31-8

Basic information

• Product Name: Methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate
• Synonyms: Methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate;4-(3,4-Dioxo-4-methoxybut-1-en-1-yl)anisole
• CAS NO: 105213-31-8
• Molecular Formula: C₁₂H₁₂O₄
• Molecular Weight: 220.22128
• Mol File: 105213-31-8.mol
• Article Data: 15

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate(105213-31-8)
• EPA Substance Registry System: Methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate(105213-31-8)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 105213-31-8(Hazardous Substances Data)

Usage

General Description

Methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate, also known as ethyl ferulate, is a chemical compound with the molecular formula C12H14O4. It is a derivative of ferulic acid, a common plant phenolic compound found in various fruits and vegetables. Methyl 4-(4-methoxyphenyl)-2-oxobut-3-enoate has been studied for its potential antioxidant, anti-inflammatory, and anti-cancer properties. It is also used in the food and cosmetic industries as a flavoring agent and fragrance ingredient. Additionally, this compound has shown promise in pharmaceutical applications, particularly in the development of novel drug formulations.

Upstream product

• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 95799-94-3 methyl 2-(trimethylsilyloxy)acrylate 
• 123-11-5 4-methoxy-benzaldehyde 
• 67-56-1 methanol 
• 860190-31-4 C₁₁H₉O₄^(1-)*K⁽¹⁺⁾ 
• 127-17-3 2-oxo-propionic acid 
• 600-22-6 pyruvic acid methyl ester 
• 17451-21-7 4-(4-methoxyphenyl)-2-oxo-3-butenoic acid 

Downstream Products

• 59670-26-7 p-methoxybenzaldehyde methyl(phenyl)hydrazone 
• 91632-76-7 N-methyl-N-phenylhydrazone of methyl 4-(4-methoxyphenyl)-2-oxo-3-butenoate 
• 1172623-52-7 (4S,4aR,8aR)-8a-[(4R)-4-ethyl-2-oxo-1,3-oxazolidin-3-yl]-4-(4-methoxyphenyl)-4a,5,6,7,8,8a-hexahydro-4H-chromene-2-carboxylic acid methyl ester 
• 1267588-61-3 (3R,4R)-methyl 4-(4-methoxyphenyl)-2-oxo-3-phenyl-3,4-dihydro-2H-pyran-6-carboxylate 
• 1313416-42-0 3-ethyl 6-methyl 2-hydroxy-4-(4-methoxyphenyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyran-3,6-dicarboxylate 
• 1321818-65-8 C₂₁H₂₁NO₄ 
• 1418950-88-5 methyl 2-hydroxy-4-(4-methoxyphenyl)-3-(4-methylphenylsulfonamido)methyl-3,4-dihydro-2H-pyran-6-carboxylate 

Relevant articles and documents

Iodine mediated a simple strategy for the synthesis of β,γ-unsaturated-α-ketoesters and its application for the synthesis of 4,5-dihydropyrazole derivatives

Abstract: Novel and efficient method for the synthesis of a series of β,γ-unsaturated-α-ketoesters under mild conditions was developed. This one-step protocol was achieved by the reaction of electron-rich aromatic aldehydes and pyruvates in the presence o

Facile synthesis of substituted diaryl sulfones: Via a [3 + 3] benzannulation strategy

A base-mediated [3 + 3] benzannulation strategy for the conversion of 1,3-bis(sulfonyl)propenes and β,γ-unsaturated α-ketoesters to diaryl sulfones has been developed. This method provides facile, metal-free and efficient access to highly substituted diaryl sulfones in good to excellent yields. In addition, the sulfonyl group could be easily removed or converted to other functional groups via an organostannane intermediate.

Catalytic Generation of Donor-Acceptor Cyclopropanes under N-Heterocyclic Carbene Activation and their Stereoselective Reaction with Alkylideneoxindoles

Formylcyclopropanes undergo activation in the presence of an N-heterocyclic carbene catalyst generating a donor-acceptor cyclopropane intermediate with the ability to undergo ring-opening followed by formal [4+2] cycloaddition with alkylideneoxindoles. This enables the direct enantio- and diastereoselective synthesis of tetrahydropyrano[2,3-b]indoles through the use of a chiral NHC catalyst. (Figure presented.).