4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine

Base Information

Chemical Name:4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine
CAS No.:931118-00-2
Molecular Formula:C₁₄H₈ClF₃N₄O
Molecular Weight:340.692
Hs Code.:

Synonyms:4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine

Chemical Property:

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Technology Process of 4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine

There total 1 articles about 4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: potassium cyanide

: 931117-99-6
4-chloro-6-(isoxazolidin-2-yl)-2-methylsulfonyl-5-(2,4,6-trifluorophenyl)pyrimidine

: 931118-00-2
4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine

Guidance literature:: With 18-crown-6 ether; In acetonitrile; at 20 ℃; for 24h;

Reference yield:

: 931118-00-2
4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine

: 931118-01-3
4-chloro-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)-2-pyrimidinecarboxamide

Guidance literature:: With dihydrogen peroxide; potassium carbonate; In water; dimethyl sulfoxide; at 20 ℃; for 16h;

Reference yield:

: 931118-00-2
4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine

: 593-56-6
N-methoxylamine hydrochloride

: 931117-97-4
N-methoxy-4-chloro-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)-2-pyrimidinecarboximidamide

Guidance literature:: 4-chloro-2-cyano-6-(isoxazolidin-2-yl)-5-(2,4,6-trifluorophenyl)pyrimidine; With sodium methylate; In methanol; at 0 ℃; for 24h;

N-methoxylamine hydrochloride; In methanol; at 20 ℃; for 6h;