4-Boc-amino-2,2-dimethylbutyric acid

Base Information

• Chemical Name: 4-Boc-amino-2,2-dimethylbutyric acid
• CAS No.: 153039-17-9
• Molecular Formula: C11H21 N O4
• Molecular Weight: 231.29
• European Community (EC) Number: 869-341-8
• Mol file: 153039-17-9.mol

Synonyms:4-Boc-amino-2,2-dimethylbutyric acid;153039-17-9;2,2-dimethyl-4-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic Acid;4-((tert-Butoxycarbonyl)amino)-2,2-dimethylbutanoic acid;4-{[(tert-butoxy)carbonyl]amino}-2,2-dimethylbutanoic acid;SCHEMBL3952768;4-(tert-Butoxy)carbonylamino-2,2-dimethylbutanoic Acid;TWMVVJUXUMIAAJ-UHFFFAOYSA-N;4-Boc-amino-22-dimethylbutyric acid;MFCD04038508;AKOS015911170;HY-W090446;s10553;AS-10348;4-(Boc-amino)-2,2-dimethyl-butanoic acid;CS-0133069;EN300-207957;4-((tert-Butoxycarbonyl)amino)-2,2-dimethylbutanoicacid;Z1505700581;Butanoic acid,4-[[(1,1-dimethylethoxy)carbonyl]amino]-2,2-dimethyl-

Chemical Property of 4-Boc-amino-2,2-dimethylbutyric acid

Chemical Property:

• Vapor Pressure: 1.74E-06mmHg at 25°C
• Boiling Point: 369.9°Cat760mmHg
• PKA: 4.81±0.10(Predicted)
• Flash Point: 177.5°C
• PSA: 75.63000
• Density: 1.065g/cm³
• LogP: 2.40290
• XLogP3: 1.7
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 231.14705815
• Heavy Atom Count: 16
• Complexity: 266

Purity/Quality:

99% ^*data from raw suppliers

4-((tert-Butoxycarbonyl)amino)-2,2-dimethylbutanoic acid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NCCC(C)(C)C(=O)O

Technology Process of 4-Boc-amino-2,2-dimethylbutyric acid

There total 1 articles about 4-Boc-amino-2,2-dimethylbutyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

tert-butyl 3,3-dimethyl-2-oxo-pyrrolidine-1-carboxylate (153039-16-8) → 2,2-dimethyl-4-[[(2-methylpropan-2-yl)oxyoxomethyl]amino]butanoic acid (153039-17-9)

Guidance literature:

With sodium hydroxide; ethanol; water; In tetrahydrofuran; at 20 ℃; for 12h;

Reference yield:

(trans,trans)-4-(3-fluoro-2-(methylphenyl)piperidine-3,5-diyl)bis(3-methoxyphenyl)methanone (937709-80-3) + 2,2-dimethyl-4-[[(2-methylpropan-2-yl)oxyoxomethyl]amino]butanoic acid (153039-17-9) → tert-butyl 4-((trans,trans)-4-(3-fluoro-2-methylphenyl)-3,5-bis(3-methoxybenzoyl)piperidin-1-yl)-3,3-dimethyl-4-oxobutylcarbamate (937709-81-4)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; HATU; In acetonitrile; at 20 ℃; for 2h;

Reference yield:

2,2-dimethyl-4-[[(2-methylpropan-2-yl)oxyoxomethyl]amino]butanoic acid (153039-17-9) → C26H41N3O6S

Guidance literature:

2,2-dimethyl-4-[[(2-methylpropan-2-yl)oxyoxomethyl]amino]butanoic acid; With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; for 0.166667h; Inert atmosphere;

tert-butyl (2-(4-(mercaptomethyl)benzamido)ethyl)carbamate; In dichloromethane; at 22 ℃; for 16h; Inert atmosphere;

upstream raw materials:

tert-butyl 3,3-dimethyl-2-oxo-pyrrolidine-1-carboxylate

Downstream raw materials:

tert-butyl 4-((trans,trans)-4-(3-fluoro-2-methylphenyl)-3,5-bis(3-methoxybenzoyl)piperidin-1-yl)-3,3-dimethyl-4-oxobutylcarbamate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 153039-17-9 4-BOC-AMINO-2,2-DIMETHYLBUTYRIC ACID

Send

Send

Metric Ton KG G Pound L ML

Send

Send