Benzyl 2-(hydroxymethyl)morpholine-4-carboxylate

Base Information

Chemical Name:Benzyl 2-(hydroxymethyl)morpholine-4-carboxylate
CAS No.:135782-20-6
Molecular Formula:C13H17 N O4
Molecular Weight:251.282
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00393040
Mol file:135782-20-6.mol

Synonyms:135782-20-6;Benzyl 2-(hydroxymethyl)morpholine-4-carboxylate;4-CBZ-2-HYDROXYMETHYLMORPHOLINE;Benzyl2-(hydroxymethyl)morpholine-4-carboxylate;(2R)-2-(Hydroxymethyl)-4-morpholinecarboxylic Acid Phenylmethyl Ester;2-hydroxymethyl-4-benzyloxycarbonyl-morpholine;SCHEMBL7020630;DTXSID00393040;JQVTXHHMCVAPDT-UHFFFAOYSA-N;AB6211;AKOS015911130;4-Benzyloxycarbonyl-2-hydroxymethylmorpholine;CS-0141744;FT-0724944;EN300-4326980;4-Morpholinecarboxylicacid,2-(hydroxymethyl)-,phenylmethyl ester

Suppliers and Price of Benzyl 2-(hydroxymethyl)morpholine-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Benzyl2-(hydroxymethyl)morpholine-4-carboxylate 95+%
1g
$ 588.00

American Custom Chemicals Corporation
4-CBZ-2-HYDROXYMETHYLMORPHOLINE 95.00%
1G
$ 1152.11

Total 12 raw suppliers

Chemical Property of Benzyl 2-(hydroxymethyl)morpholine-4-carboxylate

Chemical Property:

Vapor Pressure:1.46E-07mmHg at 25°C
Boiling Point:413°Cat760mmHg
PKA:14.36±0.10(Predicted)
Flash Point:203.6°C
PSA：59.00000
Density:1.223g/cm³
LogP:0.95420
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:251.11575802
Heavy Atom Count:18
Complexity:266

Purity/Quality:

99% ^*data from raw suppliers

Benzyl2-(hydroxymethyl)morpholine-4-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COC(CN1C(=O)OCC2=CC=CC=C2)CO

Technology Process of Benzyl 2-(hydroxymethyl)morpholine-4-carboxylate

There total 3 articles about Benzyl 2-(hydroxymethyl)morpholine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 501-53-1,94274-21-2
benzyl chloroformate

: 103003-01-6
morpholin-2-ylmethanol

: 135782-20-6,500702-97-6
2-Hydroxymethyl-4-benzyloxycarbonyl-morpholine

Guidance literature:: morpholin-2-ylmethanol; With sodium hydrogencarbonate; In tetrahydrofuran; water; for 0.0833333h;

benzyl chloroformate; In tetrahydrofuran; water; for 3h;

Reference yield:

: 40987-24-4,943442-96-4
R,S-2-hydroxymethyl-4-benzylmorpholine

: 501-53-1,94274-21-2
benzyl chloroformate

: 135782-20-6,500702-97-6
2-Hydroxymethyl-4-benzyloxycarbonyl-morpholine

Guidance literature:: With hydrogen; triethylamine; palladium on activated charcoal; Yield given. Multistep reaction;
DOI:10.1016/S0040-4039(00)79702-4