2-(4-Chlorophenyl)ethanimidamide hydrochloride

Base Information

• Chemical Name: 2-(4-Chlorophenyl)ethanimidamide hydrochloride
• CAS No.: 55154-90-0
• Molecular Formula: C8H10Cl2N2
• Molecular Weight: 168.626
• Hs Code.: 2925290090
• DSSTox Substance ID: DTXSID90540581
• Mol file: 55154-90-0.mol

Synonyms:2-(4-chlorophenyl)ethanimidamide hydrochloride;6487-93-0;55154-90-0;2-(4-CHLOROPHENYL)ACETIMIDAMIDE HYDROCHLORIDE;4-Chlorobenzeneethanimidamide Hydrochloride;2-(4-chlorophenyl)ethanimidamide;hydrochloride;MFCD06761714;2-(4-CHLORO-PHENYL)-ACETAMIDINE HYDROCHLORIDE;2-(4-Chloro-phenyl)-acetamidine HCl;SCHEMBL216057;DTXSID90540581;JVWYWIOGQGTDGZ-UHFFFAOYSA-N;AKOS005257779;AB29080;FS-1004;2-(4-chloro-phenyl)acetamidine hydrochloride;CS-0454658;EN300-7870447;2-(4-CHLOROPHENYL)ACETIMIDAMIDEHYDROCHLORIDE;(4-Chlorophenyl)ethanimidamide--hydrogen chloride (1/1)

Chemical Property of 2-(4-Chlorophenyl)ethanimidamide hydrochloride

Chemical Property:

• Vapor Pressure: 0.000403mmHg at 25°C
• Melting Point: 116-117 °C
• Boiling Point: 311.9 °C at 760 mmHg
• PKA: 11.69±0.40(Predicted)
• Flash Point: 142.5 °C
• PSA: 49.87000
• Density: 1.24±0.1 g/cm3(Predicted)
• LogP: 2.61850
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 204.0221037
• Heavy Atom Count: 12
• Complexity: 139

Purity/Quality:

98%Min ^*data from raw suppliers

2-(4-Chlorophenyl)ethanimidamide hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1CC(=N)N)Cl.Cl

Technology Process of 2-(4-Chlorophenyl)ethanimidamide hydrochloride

There total 3 articles about 2-(4-Chlorophenyl)ethanimidamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R)-2-Phenoxy-1-propylamine (6437-49-6) + toluene-4-sulfonic acid (104-15-4) → 4-chlorophenylethanamidine (55154-90-0)

Guidance literature:

With nitrogen; In ethanol; benzene;

Reference yield:

p-chlorobenzyl cyanide (140-53-4) → 4-chlorophenylethanamidine (55154-90-0)

Guidance literature:

With trimethylaluminum; ammonium chloride; In toluene;

DOI:10.1016/S0960-894X(01)00410-3

Reference yield:

→ 4-chlorophenylethanamidine (55154-90-0)

Guidance literature:

/Z0703710271/, NH3-Saettigung (ueber Nacht stehen lassen);

upstream raw materials:

p-chlorobenzyl cyanide

(R)-2-Phenoxy-1-propylamine

toluene-4-sulfonic acid

Downstream raw materials:

5-chloro-3-(4-chlorobenzyl)-1,2,4-thiadiazole

4-amino-N-[3-(4-chloro-benzyl)-[1,2,4]thiadiazol-5-yl]-benzenesulfonamide