1-(3'-Trifluoromethylbiphenyl-3-YL)ethanone

Base Information

Chemical Name:1-(3'-Trifluoromethylbiphenyl-3-YL)ethanone
CAS No.:352032-25-8
Molecular Formula:C₁₅H₁₁F₃O
Molecular Weight:264.247
Hs Code.:2914790090
DSSTox Substance ID:DTXSID60382238
Nikkaji Number:J1.536.067D
Wikidata:Q82173549
Mol file:352032-25-8.mol

Synonyms:1-(3'-TRIFLUOROMETHYLBIPHENYL-3-YL)ETHANONE;352032-25-8;1-[3-[3-(trifluoromethyl)phenyl]phenyl]ethanone;DTXSID60382238;HHBPDGRNRIYQEL-UHFFFAOYSA-N;AKOS000124572;3-Acetyl-3'-(trifluoromethyl)biphenyl;BB 0222575;1-(3'-trifluoromethyl[1,1'-biphenyl]-3-yl)ethanone;1-[3'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]ethanone;1-[3'-(Trifluoromethyl)[1,1'-biphenyl]-3-yl]ethan-1-one

Suppliers and Price of 1-(3'-Trifluoromethylbiphenyl-3-YL)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(3'-TRIFLUOROMETHYLBIPHENYL-3-YL)ETHANONE 95.00%
5MG
$ 497.46

Total 9 raw suppliers

Chemical Property of 1-(3'-Trifluoromethylbiphenyl-3-YL)ethanone

Chemical Property:

PSA：17.07000
LogP:4.57500
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:264.07619946
Heavy Atom Count:19
Complexity:324

Purity/Quality:

99% ^*data from raw suppliers

1-(3'-TRIFLUOROMETHYLBIPHENYL-3-YL)ETHANONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1=CC=CC(=C1)C2=CC(=CC=C2)C(F)(F)F

Technology Process of 1-(3'-Trifluoromethylbiphenyl-3-YL)ethanone

There total 3 articles about 1-(3'-Trifluoromethylbiphenyl-3-YL)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1092513-16-0
3-acetylphenyl methanesulfonate

: 1423-26-3
(meta-(trifluoromethyl)phenyl)boronic acid

: 352032-25-8
1-(3'-(trifluoromethyl)biphenyl-3-yl)ethanone

Guidance literature:: With potassium phosphate; dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; palladium diacetate; In tert-Amyl alcohol; at 20 - 110 ℃; Inert atmosphere;
DOI:10.1021/ol9015892

Reference yield: 86.0%

: 401-81-0
m-trifluoromethylphenyl iodide

: 2142-63-4
1-(3-Bromophenyl)ethanone

: 352032-25-8
1-(3'-(trifluoromethyl)biphenyl-3-yl)ethanone

Guidance literature:: m-trifluoromethylphenyl iodide; With TurboGrignard; In tetrahydrofuran; at -20 ℃; for 1h; Inert atmosphere;

With lithium chlorozincate; In tetrahydrofuran; Inert atmosphere;

1-(3-Bromophenyl)ethanone; With bis(dibenzylideneacetone)-palladium⁽⁰⁾; ruphos; In tetrahydrofuran; at 25 ℃; for 0.0833333h; Inert atmosphere;
DOI:10.1021/ol1007026

Reference yield: 75.0%

: 2142-63-4
1-(3-Bromophenyl)ethanone

: 1423-26-3
(meta-(trifluoromethyl)phenyl)boronic acid

: 352032-25-8
1-(3'-(trifluoromethyl)biphenyl-3-yl)ethanone

Guidance literature:: (meta-(trifluoromethyl)phenyl)boronic acid; Dowex resin (ammonium hydroxide-form); In tetrahydrofuran;

1-(3-Bromophenyl)ethanone; With Dowex resin (ammonium bromide-form); palladium diacetate; In water; at 20 ℃; for 17h; Further stages.;
DOI:10.1039/b101156l