5,7-DIMETHYL-3-OXO-2-PHENYL-3H-PYRAZOLO[1,2-A]PYRAZOL-4-IUM-1-OLATE

Base Information

• Chemical Name: 5,7-DIMETHYL-3-OXO-2-PHENYL-3H-PYRAZOLO[1,2-A]PYRAZOL-4-IUM-1-OLATE
• CAS No.: 76434-58-7
• Molecular Formula: C₁₄H₁₂N₂O₂
• Molecular Weight: 240.261
• Hs Code.: 2933998090
• Mol file: 76434-58-7.mol

Synonyms:anhydro-5,7-dimethyl-1-hydroxy-3-oxo-2-phenylpyrazolo<1,2-a>pyrazolium hydroxide

Chemical Property of 5,7-DIMETHYL-3-OXO-2-PHENYL-3H-PYRAZOLO[1,2-A]PYRAZOL-4-IUM-1-OLATE

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

5,7-Dimethyl-3-oxo-2-phenyl-3H-pyrazolo[1,2-a]pyrazol-4-ium-1-olate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,7-DIMETHYL-3-OXO-2-PHENYL-3H-PYRAZOLO[1,2-A]PYRAZOL-4-IUM-1-OLATE

There total 6 articles about 5,7-DIMETHYL-3-OXO-2-PHENYL-3H-PYRAZOLO[1,2-A]PYRAZOL-4-IUM-1-OLATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-phenylmalonic acid dihydrazide (25457-59-4) + acetylacetone (123-54-6,81235-32-7) → anhydro-5,7-dimethyl-1-hydroxy-3-oxo-2-phenylpyrazolo<1,2-a>pyrazolium hydroxide (76434-58-7)

Guidance literature:

In ethanol; at 20 ℃; for 14h;

DOI:10.1002/jhet.5570420217

Reference yield: 74.0%

3,5-dimethyl-1H-pyrazole (67-51-6) + 2-Phenyl-propanedioyl dichloride (37818-48-7) → anhydro-5,7-dimethyl-1-hydroxy-3-oxo-2-phenylpyrazolo<1,2-a>pyrazolium hydroxide (76434-58-7)

Guidance literature:

In ethyl acetate; at 40 ℃; for 0.5h;

Reference yield: 62.0%

3,5-dimethyl-1H-pyrazole (67-51-6) + diethyl 2-phenylmalonate (83-13-6) → anhydro-5,7-dimethyl-1-hydroxy-3-oxo-2-phenylpyrazolo<1,2-a>pyrazolium hydroxide (76434-58-7)

Guidance literature:

at 285 ℃; for 0.25h;

DOI:10.1055/s-1989-27341

upstream raw materials:

3,5-dimethyl-1H-pyrazole

2-Phenyl-propanedioyl dichloride

diethyl 2-phenylmalonate

phosgene

Downstream raw materials:

N¹,N³,2-triphenylmalonamide

2-phenyl-N¹,N³-di-m-tolylmalonamide

N¹,N³-bis(4-chlorophenyl)-2-phenylmalonamide

anhydro-2-(4-bromophenyl)-5,7-dimethyl-1-hydroxy-3-oxopyrazolo<1,2-a>pyrazolium hydroxide