37818-48-7

Upstream product

• 2613-89-0 phenylmalonic acid 
• 79-37-8 oxalyl dichloride 
• 103-80-0 phenylacetyl chloride 
• 101-97-3 Ethyl 2-phenylethanoate 
• 140-29-4 phenylacetonitrile 
• 7147-33-3 2-oxo-3-phenylbutanedioic acid diethyl ester 
• 616-75-1 2-benzylmalonic acid 

Downstream Products

• 101578-38-5 1-acetyl-2-(1-methyl-[4]piperidyl)-4-phenyl-pyrazolidine-3,5-dione 
• 141097-96-3 1,3-dimethyl-5-phenyl-2-thioxo-dihydro-pyrimidine-4,6-dione 
• 101732-04-1 3,5-dioxo-2,4-diphenyl-pyrazolidine-1-carboxylic acid ethyl ester 
• 68823-24-5 2-Oxo-3-phenyl-2H-pyrido<2,1-b><1,3>oxazin-5-ium-4-olat 
• 26907-10-8 2-benzhydrylidene-3-methyl-5-phenyl-[1,3]oxazinane-4,6-dione 
• 68823-16-5 2-(4-chloro-phenyl)-3-methyl-4,6-dioxo-5-phenyl-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 68823-22-3 2-(4-methoxy-phenyl)-4,6-dioxo-3,5-diphenyl-5,6-dihydro-4H-[1,3]oxazinium betaine 
• 76434-58-7 anhydro-5,7-dimethyl-1-hydroxy-3-oxo-2-phenylpyrazolo<1,2-a>pyrazolium hydroxide 
• 37899-65-3 2-Phenyl-malonic acid ethyl ester 3,4,7-trioxo-2,5,6-triphenyl-cyclohepta-1,5-dienyl ester 
• 37818-44-3 Propionic acid 3,4,7-trioxo-2,5,6-triphenyl-cyclohepta-1,5-dienyl ester 
• 37818-46-5 Benzoic acid 3,4,7-trioxo-2,5,6-triphenyl-cyclohepta-1,5-dienyl ester 
• 37818-41-0 Acetic acid 3,4,7-trioxo-2,5,6-triphenyl-cyclohepta-1,5-dienyl ester 
• 37818-43-2 Chloro-acetic acid 3,4,7-trioxo-2,5,6-triphenyl-cyclohepta-1,5-dienyl ester 
• 37818-45-4 Phenyl-acetic acid 3,4,7-trioxo-2,5,6-triphenyl-cyclohepta-1,5-dienyl ester 

Relevant academic research and scientific papers

Carboxylate-Driven Supramolecular Assemblies of Protonated meso-Aryl-Substituted Dipyrrolylpyrazoles

Dipyrrolylpyrazole (dpp) derivatives possessing an aryl ring at the pyrazole 4-position were synthesized. Upon protonation, modified dpp derivatives formed a variety of assembled structures through complexation with carboxylates, as observed by single-cry

Mesoionic pyrido[1,2-a]pyrimidinones: Discovery of dicloromezotiaz as a lepidoptera insecticide acting on nicotinic acetylcholine receptors1,2

A novel class of mesoionic pyrido[1,2-a]pyrimidinones has been discovered with exceptional insecticidal activity controlling a number of insect species. In this communication, we report the part of the optimization program that led to the identification o

All-Carbon [3+3] Oxidative Annulations of 1,3-Enynes by Rhodium(III)-Catalyzed C-H Functionalization and 1,4-Migration

1,3-Enynes containing allylic hydrogens cis to the alkyne function as three-carbon components in rhodium(III)-catalyzed, all-carbon [3+3] oxidative annulations to produce spirodialins. The proposed mechanism of these reactions involves the alkenyl-to-ally

A stable Janus bis(maloNHC) and its zwitterionic coinage metal complexes

The first stable dianionic Janus-type bis(maloNHC) was isolated and characterized. Details on the chemistry of this biscarbene with respect to its ability to support catalytically relevant metal complexes are provided. The molecular structures of two dinu

HETEROARYL LINKED QUINOLINYL MODULATORS OF RORyt

The present invention comprises compounds of Formula I. wherein: R1, R2, R3, R4, R5, R6, R7, R8, and R9 are defined in the specification. The invention also comprises a method of treating or ameliorating a syndrome, disorder or disease, wherein said syndrome, disorder or disease is rheumatoid arthritis or psoriasis. The invention also comprises a method of modulating RORγt activity in a mammal by administration of a therapeutically effective amount of at least one compound of claim 1.

Preparation of arylpropynamides and their reaction with malonyl acid derivatives

Synthesis of arylpropynamides and their reactions with different malonic acid derivatives is described. Treatment of arylpropynamides with unsubstituted malonyl chloride furnished N-(3-arylprop-2-ynoyl)-6-chloro-4-hydroxy-2-oxo-2H- pyran-3-carboxamides; m

Total synthesis of monocyclic pyrimidinium betaines with fatty alkyl chains

Seven betaines were prepared by condensation of N,N'-diphenylamidines with malonic acid derivatives. The amidines were made via a multistep synthesis, starting from their corresponding fatty acids. Malonyl chloride and dipentachlorophenyl phenylmalonate, two derivatives of malonic acid, were obtained from malonic acid and benzyl chloride, respectively. Most of the products were characterized by IR, UV, 1H and 13C NMR. Biological assays of the synthesized betaines revealed their good antibacterial and antifungal activities against the Pseudomonas aeruginosa, Bacillus subtilis and Mucor ramannianus and an activity against Candida albicans.

MIXTURES OF MESOIONIC PESTICIDES

Disclosed are compositions comprising (a) at least one compound selected from compounds of Formula (1), N-oxides, and salt thereof, wherein R1 is phenyl optionally substituted with up to 5 substituents independently selected from R3,

ESTER DERIVATIVE AND MEDICINAL USE THEREOF

A therapeutic agent for hyperlipidemia which has no side effects on the liver unlike conventional MTP inhibitors and has excellent MTP inhibitory activity. Also, provided is an ester compound represented by the general formula (1): or a pharmaceutically a

ESTER COMPOUND AND MEDICINAL USE THEREOF

A novel therapeutic agent for hyperlipidemia, which is an ester compound represented by the formula (1") (wherein ???R1 and R2 are each hydrogen atom or optionally substituted aryl, etc.; ???X is -COO- or -CON(R10)-; ???R3 and R4 are each hydrogen atom, C1-C6 alkyl or C1-C6 alkoxy, etc.; ???R5, R6 and R7 are each hydrogen atom, C1-C6 alkyl or C1-C6 alkoxy, etc.; ???R8 and R9 are each independently hydrogen atom, C1-C6 alkyl, -CON(R18)(R19) or -COO(R20), etc.; ???ring A, ring B and ring C are each independently aryl or heterocycle residue, etc.; ???Alk1 and Alk2 are each independently alkanediyl, etc.; ???l and m are each an integer of 0 or 1 to 3) or a prodrug thereof, or a pharmaceutically acceptable salt of either. The therapeutic agent selectively inhibits MTP in the small intestine, thus causes no such side effect as a fatty liver.